MMSC 423 Exam 1 (100% Accurate Solutions)

Fibrinogen correct answers main substrate of the coagulation system Sodium Citrate correct answers most common anticoagulant Serum correct answers fluid obtained when coagulated blood (red top tube) has been centrifuged fibrinogen is absent Plasma correct answers fluid obtained when anticoagulated blood (purple top tube) has been centrifuged fibrinogen is present Hemostasis correct answers arrest of bleeding by spontaneous formation of the hemostatic platelet plug Primary Hemostasis correct answers endothelium has been cut platelet adhesion, platelet aggregation, platelet secretion platelets congregate at breach in skin and form platelet plug Secondary Hemostasis correct answers fibrinogen turns to fibrin activation of coagulation cascade forms fibrin mesh which stabilizes platelet plug from primary hemostasis Endothelial Cells correct answers rhomboid provide smooth inner surface of blood vessel - promoting blood flow and presenting turbulence that could activate platelets form physical barrier secrete TFPI, TPA express EPCR, cell membrane thrombomodulin Subendothelial Connective Tissue correct answers collagen and fibroblasts in veins collagen, fibroblasts, and smooth muscle in arteries Collagen correct answers procoagulant binds to platelets binds to factor XII participates in intrinsic coagulation cascade main structural protein in ECM 25-30% of protein in the body amino acids form a triple helix structure Heparan Sulfate correct answers anticoagulant that enhances antithrombin TFPI correct answers anticoagulant that inhibits factor Xa , VIIa, and TF synthesized by endothelial cells