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Galen NUR 210 Exam 1 Modules 1-3 with 100% Correct Answers | Latest Version (2024/2025) Expert Verified

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Galen NUR 210 Exam 1 Modules 1-3 with 100% Correct Answers | Latest Version (2024/2025) Expert Verified

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  • September 5, 2023
  • March 6, 2025
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Galen NUR 210 Exam 1 Modules 1-3 with 100%
Correct Answers | Latest Version (2024/2025)
Expert Verified
Pharmacokinetics..-..
Correct Answer-The..process..in..which..medications..move..through..the..body

What..are..the..4..phases..of..pharmacokinetics?..-..
Correct Answer-absorption,..distribution,..metabolism,..excretion

Absorption..-..
Correct Answer-
happens..with..drug..movement..from..the..GI..tract..into..the..bloodstream...Most..meds..are
..taken..by..mouth.


Oral..absorption..-..
Correct Answer-
Takes..awhile..to..get..absorbed..because..it..has..to..go..through..the..GI..system

Usually..takes..2-4..hours
•Enteric..coated
.. aspirin..-..hard..on..stomach
.. can..not..crush..pill
•Extended..release
.. absorbed..in..the..small..intestine


IM..absorption..-..
Correct Answer-Absorbed..1-2..hours

IV..absorption..-..
Correct Answer-Absorbed..30-60..minutes

dissolution..-..
Correct Answer-
Dissolution..happens..when..a..po..medication..breaks..down..into..particles,..disintegrates,..
and..dissolves..to..combine..with..liquid..so..absorption..from..the..GI..tract..into..the..bloodst
ream..occurs.
Liquid..medications..are..absorbed..faster..than..solids...Food..can..interfere..with..the..absor
ption..of..drugs.

Drugs..that..resist..dissolution..-..
Correct Answer-

,Parenteral..medications..(SL,..eyedrops,..inhalants,..transdermal)..do..not..pass..through..the
..GI..tract.
Enteric..coated..medications..are..designed..to..resist..disintegration..until..the..pill..reaches..the.
.small..intestine...EC..and..sustained..release..meds..should..not..be..crushed.


Factors..that..affect..absorption..-..
Correct Answer-•Lack..of..muscle..and..increased..fat..changes..medicine..absorption
•Food..consumption..-..will..change..medicine..potency..(delayed)
•Stress..-..Exercise,..medicine..goes..to..muscle
•pH..-..Medicine..is..made..for..acidic..environments
•Antacid..changes..absorption

•Taken..alone..so..it..doesn't..change..the..action

Excipients..-..
Correct Answer-
Fillers..and..other..substances..that..make..up..tablets..as..a..pill..is..not..100%..drug.
Sometimes..an..excipient..enhances..the..absorption..of..a..drug..such..as..with..PCN,..which..i
s..not..well..absorbed..from..the..GI..tract.
Adding..Na..to..PCN,..which..makes..it..penicillin..sodium,..will..increase..the..absorption
..of..PCN


first..pass..effect..-..
Correct Answer-
•the..oral..drugs..go..to..liver..via..portal..vein..where..some..of..the..drug..becomes..inactive
•Only..happens..with..oral..medications

delayed..gastric..emptying..-..
Correct Answer-Food..doesn't..move..like..it..should

Distribution..-..
Correct Answer-
refers..to..the..movement..of..the..drug..from..the..circulation..to..body..tissues

Factors..affecting..distribution..-..
Correct Answer--blood..flow..to..tissues
-protein..binding
-blood..brain..barrier
-drug's..affinity..to..the..tissue

protein..binding..-..
Correct Answer-Drugs..bind..with..proteins..in..blood
Some..drugs..are..highly..protein..bound..and..other..are..weakly..protein..bound

free..drugs..-..
Correct Answer-drugs..not..bound..to..protein

, Drug..Toxicity..-..
Correct Answer--
Two..highly..protein..bound..drugs..compete..and..one..might..accumulate..and..cause..a..toxicity
-
it..is..important..to..know..if..you..are..administering..highly..protein..bound..medications..and
..monitor..albumin..levels..in..patients..with..liver..or..kidney..disease.
-
Some..drugs..that..are..highly..protein..bound..include:..Warfarin..Furose
mide
Diazepam

Drug..distribution..and..albumin..-..
Correct Answer--A..decrease..in..albumin..levels..decrease..the..protein-
binding..sites,..which..means..more..of..the..free..drug..is..circulated.
-This..can..be..fatal..with..some..meds.
-
Free..drugs..are..those..not..bound..to..protein,..which..means..they..are..active..in..the..body..a
nd..cause..a..pharmacologic..response.
-
Older..adults,..malnourished..individuals,..and..those..with..liver..or..kidney..disease..have..low..albu
min..levels.

Blood..Brain..Barrier..(BBB)..-..
Correct Answer--The..BBB..protects..the..brain..from..most..drugs.

-Some..meds..are..able..to..cross..the..BBB..such..as..benzodiazepines.
-
Drugs..can..cross..the..placenta..and..cause..spontaneous..abortion..or..alter..fetal..growth..and..devel
opment.

Metabolism..-..
Correct Answer-•Chemically..changes..drug..to..a..form..that..can..be..excreted
•Liver..primary..site

half-life..-..
Correct Answer-•the..time..it..takes..for..the..drug..in..the..body..to..be..reduced..by..half

Loading..dose..-..
Correct Answer-
use..of..a..higher..dose..than..what..is..usually..used..for..treatment..to..allow..the..drug..to..reac
h..the..critical..concentration..(therapeutic..level)..sooner
•Blood..thinner
•Antibiotic

Exceretion..-..
Correct Answer-
the..removal..of..waste..products..from..medications..which..is..done..mainly..through..the..ki

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