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Immunology Exam 1 (Microbiology 5122 OSU AU14) Questions And Answers
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Immunology Exam 1 (Microbiology 5122 OSU AU14) Questions And Answers
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Immunology Exam 1 (Microbiology 5122 OSU AU14 ) Questions And Answers What is the most important function of the immune system? Answer- Confers protection against pathogensWhat two key components is the immune system comprised of? Answer- Specialized cells (phagocytes, lymphocytes), and soluble mediators (complement, cytokines, chemokines).
Where are immune cells derived? Answer- From progenitor stem cells made in the bone marrow.
What cell type is the first line of immune defense versus invaders? Answer- Phagocytes
What are the functions of phagocytes? Answer- 1. Engulf and internalize pathogen
2. Digest/destroy using toxic substances
3. Present antigen to lymphocytes triggering activation and acquired immunity.
Which immune cells are specific to Acquired Immunity? Answer- B cells and T cells
What type of antigens do B cells recognize and by what receptor? Answer- Soluble antigens by expressed antibodies on the cell surface.
What type of antigens do T cells recognize and by what receptor? Answer- Antigens
presented by phagocytes and by the T Cell Receptor (TCR)
What is an epitope? Answer- The part of the antigen that binds to antibody or TCR and is very specific.
What antigen type can trigger an immune response without any other mediators present? Answer- Immunogen
Which type of T Cell secretes cytokines (soluble factors) and aids other immune cells
as T Helper Cells? Answer- CD4+ T Cells
Which type of T Cell recognizes and destroys other cells that are infected or cancerous? Answer- CD8+ T Cells
What are the two key features of T and B Cell responses? Answer- Specificity and Memory
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