NURS 615: ADVANCED PHARMACOTHERAPEUTICS Paper 4 Questions and answers 2023

NURS 615: ADVANCED PHARMACOTHERAPEUTICS Paper 4 Questions and answers 2023 What is Tiotropium (SPIRIVA) used to treat? Used in the management/ maintenance treatment of chronic obstructive pulmonary disease (COPD) which includes chronic bronchitis and emphysema. What is the drug classification of Tiotropium? It is a long-acting, 24H anticholinergic-bronchodilator. It is a muscurinic receptor antagonist, often referred to as an antimuscurinic or anticholinergic agent. What is the mechanism of action of Tiotropium (SPIRIVA) It does not display selectivity for specific muscarinic receptors, when topically applied it acts mainly on M3 muscarinic receptors[8] located on smooth muscle cells and submucosal glands. This leads to a reduction in smooth muscle contraction and mucus secretion and thus produces a bronchodilatory effect. What are the adverse effects with montelukast (Singular) Anxiety, aggression, depression, suicidal thoughts, What patient teaching should accompany the prescription of montelukast (Singulair)? Teach pt regarding adverse effect about aggression , depression suicidal thoughts that could occur