CPIA Exam Questions & Answers: Updated Solution: A+ Guide Solution

What does the Public Service Policy on Humane Care and Use of Laboratory Animal (PHS Policy) implement? (Ans- the Health Research Extension Act of 1985 The Health Research Extension Act of 1985 directs ______ to establish guidelines for the proper care and treatment of animals used in research (Ans- the Secretary of Health and Human Services In 1986, the PHS Policy incorporated the ________ by the Interagency Research Animal Committee and adopted by US Government agencies that use vertebrate animals (Ans- U.S. Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training IACUC membership requirements for PHS Assurance (Ans- 5 members: One veterinarian (training/experience in lab animal medicine) One scientist (experience in research) One nonscientific member One not affiliated member PHS Policy mandates that animal care and use programs must operate in accordance with four specific laws and guidelines (Ans- 1. The Animal Welfare Act 2. United States Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training 3. The Guide for the Care and Use of Laboratory Animals 4. AVMA Guidelines for the Euthanasia of Animals Code of Federal Regulations, Title 9, Chapter 1, Subchapter A, Parts 1, 2, and 3 (Ans- Animal Welfare Regulations that are implemented by the USDA/APHIS/AC Clarified humane care, minimization of pain and distress, consideration of alternatives, institutional animal care and use committees, psychological well-being of primates, and exercise for dogs (Ans- 1985 amendments to the AWA Which term is defined in the Guide as "all measures to control known or unknown infections in laboratory animals." a. Biosecurity b. Stabilization c. Quarantine d. Biosafety (Ans- a. Biosecurity Which of the following statements about multiple survival surgical procedures on a single animal is TRUE? a. The Guide's definition of "major" surgery is rigid, and does not provide for any interpretation by the veterinarian or the IACUC. b. When USDA-covered species are used, the Animal Welfare Regulations' definition of "major" surgery takes precedence. c. The Animal Welfare Regulations allow for the interpretation of "major" surgery to be evaluated on a case-by-case basis by the IACUC. d. The Guide's requirement that multiple major survival surgeries must be scientifically justified and included in the IACUC-approved protocol only applies to non-rodent mammals. (Ans- b. When USDA-covered species are used, the Animal Welfare Regulations' definition of "major" surgery takes precedence. Animals using which type of thermoregulation depend mostly on environmental temperature to maintain their internal physiology? (Ans- Poikilothermic Which should be provided in the environment of