PHARMACOLOGY AND NURSING PROCESS: PHARMACOLOGY CALCULATIONS FINAL EXAM
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PHARMACOLOGY
Institution
PHARMACOLOGY
1. How many milliliter of U-100 insulin should be used to obtain 50 units of insulin?
a. 5 mL b. 50 mL c. 0.5 mL d. 500 mL
A 2. How many drops would be prescribed in each dose of a liquid medicine if 20 mL contained 60 doses? The dispensing dropper calibrates 35 gtts per mL.
a. 12 gtts b. 15 gt...
Pharmaceutical Calculation
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C 1. How many milliliter of U-100 insulin should be used to obtain 50 units of insulin?
a. 5 mL b. 50 mL c. 0.5 mL d. 500 mL
A 2. How many drops would be prescribed in each dose of a liquid medicine if 20 mL contained 60 doses? The
dispensing dropper calibrates 35 gtts per mL.
a. 12 gtts b. 15 gtts c. 8 gtts d. 23 gtts
B 3. How many milligrams of a drug will be needed to prepare 74 dosage forms if each is to contain 1/10 grain?
a. 58 mg b. 480 mg c. 4800 mg d. 4.8mg
D 4. If a pint of a certain liquid weighs 9200 grains, what is the specific gravity of the liquid?
a. 1.0 b. 1.32 c. 1.276 d. 1.26
B 5. How many grams of dextrose are required to prepare 4500 L of a 5% solution?
a. 80,000 g b. 1.82 f3 c. 4 f3 d. 8 f3
B 6. How many grams of a drug substance should be dissolved in 250 mL of water to make a 5% (w/w) solution?
a. 9.6 g b. 13.16 g c. 60 g d. 10 g
A 7. Convert 5% to mg/mL:
a. 50 mg/mL b. 500 mg/mL c. 5000 mg/mL d. 5 mg/mL
B 8. In what proportion should alcohols of 90% and 50% strengths should be mixed to make 70% alcohol?
a. 3 parts / 5 parts b. 1 part / 1 part c. 5 parts / 4 parts d. 4 parts / 5 parts
A 9. How many milliliters of two liquids with specific gravities of 0.950 and 0.875 should be used to prepare 1500
mL of a liquid having a specific gravity of 0.925?
a. 1000 mL (sp gr 0.950) c. 500 mL (sp gr 0.950)
500 mL (sp gr 0.875) 1000 mL (sp gr 0.875)
b. 2250 mL (sp gr 0.950) d. 1125 mL (sp gr 0.950)
1125 mL (sp gr 0.875) 2250 mL (spgr 0.875)
A 10.Zinc chloride is a three-ion electrolyte, dissociating 80% in a certain concentration. Calculate its dissociation
factor (I):
a. 2.6 b. 1.6 c. 2.9 d. 3
A 11. If 10 mg of a drug are added to a 500 mL large-volume parenteral fluid, what should be the rate of flow,
in mL/hour, to deliver 1 mg of drug per hour?
a. 50 mL/hour b. 20 mL/hour c. 500 mL/hour d. 5 mL/hour
B 12. How many milliequivalents are there in 15 mL of a 50% MgSO4 solution? (mol. Wt.
246) a. 6.097 mEq b. 60.97 mEq c. 6.96 mEq d. 69.7 mEq
B 13. You are directed to weigh 10 grams of a substance so as to limit the error to 0.2%. Calculate the maximum
potential error, in terms of grams, that you would not be permitted to exceed.
a. 0.05 g b. 0.02 g c. 0.002 g d. 0.2 g
B 14. A prescription is to be taken as follows: 1 tablet q.i.d. the first day; 1 tablet t.i.d. the second day; 1 tablet b.i.d.
x 5 d; and 1 tablet q.d. thereafter. How many tablets should be dispensed to equal a 3-day supply?
a. 18 tablets b. 40 tablets c. 22 tablets d. 47 tablets
B 15. Tetracycline has been shown to form a calcium complex in bone-forming tissue in infants given oral
tetracycline in doses of 0.011 g/lb body weight every 6 hours. Express the dose in terms of milligrams per
kilogram of body weight.
a. 5 mg/Kg b. 24.2 mg/Kg c. 25 mg/Kg d. 11 mg/Kg
A 16. How many colchicines tablets, each containing 600 mcg, may be prepared from 30 g of colchicines?
a. 50,000 tablets b. 20,000 tablets c. 20 tablets d. 50 tablets
D 17. Digitoxin is available for parenteral pediatric use in a concentration of 0.1mg/mL. How many milliliters
would provide dose of 40 mcg?
a. 0.04 mL b. 40 Ml c. 40 mL d. 0.4 mL
A 18. Nitrostat Sublingual tablets are available as 1/200-gr tablets. What is the approximate equivalent in
milligrams?
a. 0.325 b. 0.077 c. 0.005 d. 0.65
B 19. Four thousand (4000) nanograms equals 4:
a. centigrams b. grams c. milligrams d. micrograms
B 20. If a physician prescribed 4 grams of aspirin to be taken by a patient daily, about how many 5-grain
tablets should the patient take each day?
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a. 500 mcg b. 300 mcg c. 5000 mcg d. 200 mcg
A 22. A commercial package contains thirty-six 200-mg tablets of ibuprofen. How many kilograms of ibuprofen
were used in the manufacture of 1000 packages of product?
a. 7.2 Kg b. 5 Kg c. 7.8 Kg d. 6.9 Kg
B 23. How many grams of ethyl estradiol are needed to prepare 2,500 tablets, each containing 50 mcg of the
medicinal substance?
a. 1.25 g b. 12.5 g c. 0.125 g d. 125 g
A 24. Pico denotes of the basic unit:
a. 10-12 b. 10-15 c. 10-18 d. 10-10
A 25. 1 milliliter is 1,000x greater than:
a. microliter b. picoliter c. nanoliter d. liter
C 26. Sudafed cough syrup contains 0.09 g of dextromethorphan hydrobromide in each fluidounce. How many
milligrams of this agent would be present in each teaspoonful dose?
a. 10 mg b. 12 mg c. 15 mg d. 20 mg
D 27. The usual dose of digoxin for rapid digitalization is a total of 1.0 mg, divide into two or more portions at
intervals of 6 to 8 hours. How many milliliters of digoxin elixir containing 50 mcg/ mL would provide this
dose?
a. 15 mL b. 10 mL c. 25 mL d. 20 mL
A 28. The dose of beclamethasone, an aerosolized inhalant, is 200 cg twice daily. The commercial inhaler delvers
50 mcg per metered inhalation and contains 200 inhalations. How many inhalers should be dispensed to a
patient if a 60-day supply is prescribed?
a. 3 b. 2 c. 4 d. 5
B 29. If a physician prescribed Keflex, 250 mg q.i.d. x 10 days, how many milliliters of Keflex suspension
containing 250 mg per 5 mL should be dispensed?
a. 250 mL b. 200 mL c. 150 mL d. 100 mL
A 30. Terpin hydrate and codeine elixir contains 60 mg of codeine per 30 mL. How much additional
codeine should be added to 180 mL of the elixir so that each teaspoonful will contain 15 mg of codeine?
a. 180 mg b. 200 mg c. 170 mg d. 190 mg
C 31. The directions intended for the patient on a prescription read 1 Tbsp a.c. and h.s. for 10 days. What is the
minimum volume the pharmacist should dispense?
a. 200 mL b. 150 mL c. 600 mL d. 450 mL
A 32. If the cost of human growth hormone is P40/mg q 4 h six times daily. How many will a 180-lb patient
receive daily?
a. 12 mg b. 164 mg c. 650 mg d. 980 mg
C 33. The pediatric dose of cefadroxil is 30mg/Kg/day. If a child was given a daily dose of 2 teaspoonfuls of
pediatric suspension containing 125 mg of cefadroxil per 5 mL, what was the weight, in pounds, of the child?
a. 19 lbs b. 17.3 lbs c. 18.3 lbs d. 18.5 lbs
A 34. A Ferrous Sulfate syrup contains 220 mg of FeSO4.7H2O per teaspoon dose. How many milligrams of
elemental iron are present in the dose? (mol wt FeSO4.7H2O = 278; at. Wt. of Fe = 55.9, s = 32.1, O = 16, H
= 1.0)
a. 44 mg b. 50 mg c. 88 mg d. 100 mg
A 35. An antacid tablet contains 80 mg off dried aluminum hydroxide gel and 20 g of magnesium trisilicate. How
many kilograms of aluminum hydroxide gel are required to manufacture 250000 bottles of the product, each
containing 100 tablets?
a. 2000 Kg b. 20,000 Kg c. 200 Kg d. 8000 Kg
B 36. An estradiol transdermal system contains in each skin patch 4 mg of estradiol and 0.3mL of alcohol. How
many liters of alcohol would be required to manufacture a half-million patches?
a. 15 L b. 150 l c. 1,500 L d. 300 L
A 37. From the ff. formula:
Benzyl benzoate 250 mL
Triethanolamine 5 mL
Purified water, to make 1000 mL
Calculate the quantity of benzyl benzoate required to make 6 fl. Oz. of benzyl benzoate lotion.
a. 45 mL b. 40 mL c. 4.5 mL d. 25 mL
A 38. If 150 mL of polyethylene glycol 400 weighs 74.1 g, what is its specific
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D 40. Cocoa butter, which is solid at room temperature and melts at 34°C, has a specific gravity of 0.86. If a
formula calls for 48 mL of theobroma oil, what would be the corresponding weight of cocoa butter to
use? a. 40 g b. 55.81 g c. 50 g d. 41.3 g
D 41. A formula for a mouth rinse contains 1/10% (w/v) of zinc chloride. How many grams of zinc chloride
should be used in preparing 25 liters of the mouth rinse?
a. 35 g b. 30 g c. 20 g d. 25 g
C 42. If a pharmacist dissolves the contents of 8 capsules, each containing 250mg of clindamycin hydrochloride,
into a sufficient amount of Ionex Astringent to prepare 120 mL of solution, what is the percentage
strength (w/v) of clindamycin hydrochloride in the prescription?
a. 1% b. 1.5% c. 1.67% d. 2%
C 43. If an intravenous dose of mannitol is 1.5% (w/v) sodium chloride solution can be made from 1 lb of sodium
chloride?
a. 50,444 mL b. 50,000 mL c. 50,400 mL d. 1,000 mL
C 44. If 10 mL f a nitroglycerin injection (5mg of nitroglycerin per milliliter) are added to make a liter
of intravenous fluid, what is the percentage (w/v) of nitroglycerin in the final product?
a. 0.025% b. 0.05% c. 0.005% d. 0.0005%
A 45. How many milliliters of resorcinol monoacetate should be used to prepare 1 pint of a 15% (v/v) lotion?
a. 71 mL b. 65 mL c. 76 mL d. 69 mL
B 46. How many liters of a mouthwash can be prepared from 100 mL of cinnamon flavor if its concentration is to
be 0.5% (v/v)?
a. 10 L b. 20 L c. 15 L d. 18 L
C 47. One pound of a fungicidal ointment contains 9.08 g of undecylenic acid. Calculate the percentage (w/w) of
undecylenic acid in the ointment.
a. 1.81% b. 1.5% c. 2% d. 2.5%
B 48. A vaginal foam contains 0.01% (w/v) of dienestrol. Express this concentration as a ratio
strength. a. 1:100 b. 1:10,000 c. 1:1,000 d. 1:100,000
A 49. A sample of white petrolatum contains 10 mg of tocopherol per kilogram as a preservative. Express the
amount of tocopherol as a ratio strength.
a. 1:100,000 b. 1:1,000 c. 1:1,000,000 d. 1:10,000
B 50. Hepatitis B immune globulin is preserved with 1:10,000 (w/v) of thimerosal. If the dose of the injection is
0.06 mL/Kg of body weight, how many micrograms of thimerosal would be contained in the dose for a 150-lb
patient?
a. 400 mcg b. 409 mcg c. 415 mcg d. 450 mcg
A 51. What is the percent concentration of cholesterol in a patient’s blood serum if the cholesterol level is
determined to be 260 mg%?
a. 2.6% b. 26% c. 0.26% d. 0.026%
B 52. If a serum sample is determined to contain 270 mg/dL of cholesterol, what is the concentration of
cholesterol (mol wt 386) in terms of millimoles per liter?
a. 6.5 mmol/L b. 6.9 mmol/L c. 69.9 mmol/L d. 5.66 mmol/L
A 53. A glucose meter shows that a patient’s blood contains 125mg% of glucose. Express this value as mg/mL.
a. 1.25 mg/mL b. 12.5 mg/mL c. 125 mg/mL d. 0.125 mg/mL
C 54. If 250 mL of a 1:800 (v/v) solution are diluted to 1000 mL, what will be the ratio strength
(v/v)? a. 1:320 b. 1:3000 c. 1: 3,200 d. 1: 32,000 DNA
B 55. If 400 ml of a 20% (w/v) solution are diluted to 2 liters, what will be the percentage strength (w/v)?
a. 8% b. 4% c. 5% d. 2%
C 56. How many milliliters of water must be added to 250 mL of a 25% (w/v) stock solution of sodium chloride
to prepare a 0.9% (w/v) sodium chloride solution?
a. 6,5100 mL b. 6,600 mL c. 6,694 mL d. 6,490 mL
C 57. How many milliliters of a syrup containing 85% (w/v) of sucrose should be mixed with 150mL of a
syrup containing 60% (w/v) of sucrose to make a syrup containing 80% (w/v) of sucrose?
a. 500 mL b. 550 mL c. 600 mL d. 650 mL
D 58. How many milliliters of 95% (w/w) sulfuric acid having a specific gravity of 1.820 should be used in
preparing 2 liters of 10% (w/v) sulfuric acid?
a. 110 mL b. 120 mL c. 114 mL d. 116 mL
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