Dit is een samenvatting over de module complexiteit en chroniciteit waar veel verschillende onderwerpen aan bod komen. Dit komt uit het 3e leerjaar van de studie fysiotherapie aan de HU.
,Pathologie
Neurologie
Incidentie Prevalentie
MS ??????????????????????????? 1:500
M.P 0,2-0,3:1000 per jaar 1:330
Multiple sclerose; aantasting myelineschede -> sclerotische plaque
geopende bloed hersenbarrière -> afbraak axonen
- Witte stof gaat verloren
- Littekens blijven over
- Kortsluiting doordat geleiding niet meer mogelijk is (binnen cel)
- Cel sterft
Beeldvorming via MRI; sclerotische plaques zichtbaar als witte vlekken
Relapse = schub = exacerbatie (=aanval)
Demyelinisatie en remyelinisatie (negatief beïnvloed door 2 ((NO. Onderstaand))
1. Oligondendrocyten
2. Fibronectine klontert samen dus moeilijk afgebroken
1. Ataxie 80% ooit een keer voor of blijvend
2. Dysarthrie
3. Mictie
4. Seksueel
5. Psychisch
6. Vermoeidheid
1. McD criteria (2010)
2. Min 2 laesies
3. Locatie en tijd
,
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