Biochemistry - Metabolism Questions With Complete Solutions

a-D-glucose + ATP --- ________ + ________ + H+ correct answer: a-D-glucose-6-phosphate + ADP For the first five steps of glycolysis, the appropriate sequence of enzymes is: a. phosphofructokinase-1 (PFK-1) b. hexokinase/glucokinase c. fructose bisphosphate aldolase d. phosphoglucoisomerase e. triose phosphate isomerase (TPI) correct answer: B, D, A, C, E Hexokinase and glucokinase belong to the kinase subclass of what class of enzymes? correct answer: transferase In the second half of the glycolytic pathway, _____ ATP molecules are produces and with the offset of _____ ATPs consumed in the first half, the net yield is ____ ATPs per glucose. correct answer: 4; 2; 2 substrate-level phosphorylation occurs in glycolysis in the reaction catalyzed by _________ and belongs to _______ class of enzymes. correct answer: phosphoglycerate kinase; transferase Which of the following amino acids provides the nucleophile in the reaction of class I aldolase? correct answer: Lysine NADH, __________ and _________ are products of glycolysis, and the NADH must be recycled to ________ before it becomes limiting in glycolysis. correct answer: ATP; pyruvate; NAD+ The oxidation of one mole of glucose by anaerobic glycolysis yields a net of: correct answer: two moles of lactate and two moles of ATP Lactate produces by anaerobic muscle tissue is: correct answer: carried by the blood to the liver for gluconeogenesis and converted to glucose Seven of the ten reactions of glycolysis are reversible (deltaG near zero) and can be used in reverse of glycolysis for gluconeogenesis. The three irreversible reactions are catalyzed by: correct answer: hexokinase, phosphofructokinase-1 (PFK-1), pyruvate kinase What of the following cannot be used as a precursor for gluconeogenesis? correct answer: Leucine Anaerobic glycolysis can produce ATP at a much faster rate than aerobic oxidative phosphorylation (T/F) correct answer: True