Pathofysiologie en pathologische biochemie (1025FBDDIE)
Summary
Samenvatting pathologische biochemie en fysiologie van de huisdieren - 16/20 behaald
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Course
Pathofysiologie en pathologische biochemie (1025FBDDIE)
Institution
Universiteit Antwerpen (UA)
uitgebreide en duidelijke samenvatting van het vak pathologische biochemie en fysiologie van de huisdieren, gegeven door professor Leroy.
Samenvatting bevat de lessen en de slides.
Ik heb hier zelf een 16/20 mee behaald.
Pathofysiologie en pathologische biochemie (1025FBDDIE)
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PATHOLOGISCHE BIOCHEMIE EN
FYSIOLOGIE VAN DE HUISDIEREN
Algemene inleiding........................................................................................................................................ 6
Wat is normaal?....................................................................................................................................................6
Terminologie:....................................................................................................................................................7
Precisie van de meting..........................................................................................................................................7
Accuraatheid/ validiteit:.......................................................................................................................................7
Diagnosestelling....................................................................................................................................................8
Klinisch redeneren.................................................................................................................................................9
Belangrijke termen................................................................................................................................................9
Vet- en koolhydraatstofwisseling................................................................................................................. 47
Algemeen............................................................................................................................................................47
Vetstofwisseling..................................................................................................................................................47
Vetzuren & lipiden...........................................................................................................................................47
Vetzuren – chemische reacties...................................................................................................................47
Vertering en absorptie van lipiden..................................................................................................................47
Darmlumen..................................................................................................................................................47
Mucosacel...................................................................................................................................................47
Mucosacel...................................................................................................................................................47
In de circulatie.............................................................................................................................................48
In de lever....................................................................................................................................................48
In de vetcel..................................................................................................................................................48
Metabolisme van vet in het lichaam...............................................................................................................49
Vluchtige vetzuren.......................................................................................................................................49
Andere vetzuren..........................................................................................................................................49
Lipoproteïnen..............................................................................................................................................49
Afwijkingen in het vetmetabolisme................................................................................................................50
Steatorrhee.................................................................................................................................................50
Adipositas....................................................................................................................................................50
Equine metabool syndroom........................................................................................................................52
Hyperlipaemie: ponys en paarden..............................................................................................................54
Laag melkvetgehalte...................................................................................................................................56
Ketonemie bij herkauwers..........................................................................................................................57
Fat cow syndrome.......................................................................................................................................62
Drachtigheidstoxomie bij schaap................................................................................................................66
Koolhydraatstofwisseling....................................................................................................................................68
Koolhydraten...................................................................................................................................................68
Resorptie.........................................................................................................................................................68
Niet-herkauwers: paard..............................................................................................................................68
Herkauwers.................................................................................................................................................68
Storingen in de koolhydraatresorptie.............................................................................................................68
resorptie testen...........................................................................................................................................68
Glucosestofwisseling...................................................................................................................................70
Hormonmale regeling van het KHD metabolisme..........................................................................................71
Insuline........................................................................................................................................................71
Glucagon......................................................................................................................................................71
Catecholamines...........................................................................................................................................71
Glucocorticoïden.........................................................................................................................................71
Afwijkingen in het KHD metabolisme.............................................................................................................72
Hyperglycemie – diabetes mellitus.............................................................................................................72
Hypoglycemie..............................................................................................................................................77
Eiwitstofwisseling........................................................................................................................................ 79
Eiwitstofwisseling & N-eliminatie.......................................................................................................................79
Algemeen.........................................................................................................................................................79
Synthese..........................................................................................................................................................79
Resorptie.........................................................................................................................................................79
Katabolisme van eiwit & N-uitscheiding.........................................................................................................79
Lichaams- en serumeiwitten...............................................................................................................................84
Plasmaeiwitten................................................................................................................................................84
Storingen van plasmaproteïne-homeostase...............................................................................................84
Serumeiwitten.................................................................................................................................................86
Mineralen.................................................................................................................................................... 88
Algemeen............................................................................................................................................................88
Kalium.................................................................................................................................................................88
Huishouding.....................................................................................................................................................88
Opname.......................................................................................................................................................88
Behoefte......................................................................................................................................................88
K+ in de darm..............................................................................................................................................88
K+ in de nier.................................................................................................................................................89
Regeling.......................................................................................................................................................89
Afwijkingen in K+ huishouding........................................................................................................................90
Hypokaliaemie.............................................................................................................................................90
Hyperkaliaemie............................................................................................................................................91
Calcium................................................................................................................................................................93
Voorkomen en functies...................................................................................................................................93
Ca-concentratie in het plasma....................................................................................................................93
Ca-concentratie in het ECW........................................................................................................................93
Ca-concentratie in de cel.............................................................................................................................93
Relatie Ca & P..............................................................................................................................................93
Relatie Ca & H+............................................................................................................................................93
Invloed van Ca op de celmembraan............................................................................................................94
Ca & celactivatie: contractie.......................................................................................................................94
Rol van Ca in andere cellen.........................................................................................................................94
Regeling van Calcemie.....................................................................................................................................95
Passieve regeling.........................................................................................................................................95
Actieve regeling...........................................................................................................................................96
Afwijkingen in de Ca-huishouding...................................................................................................................97
hypocalciemie..............................................................................................................................................97
Hypercalcemie...........................................................................................................................................102
Fosfor................................................................................................................................................................103
Functies.........................................................................................................................................................103
Afvoer............................................................................................................................................................103
Regeling P gehalte.........................................................................................................................................103
Afwijkingen in P metabolisme.......................................................................................................................104
Bij chronisch té lage opname....................................................................................................................104
Postparturiënt hemoglobinurie................................................................................................................104
Hyperfosfatemie........................................................................................................................................104
Magnesium.......................................................................................................................................................105
Voorkomen & functie....................................................................................................................................105
Regeling van Mg huishouding.......................................................................................................................105
Afwijkingen van Mg huishouding..................................................................................................................105
Hypomagnesemie......................................................................................................................................105
Ijzer....................................................................................................................................................................107
Voorkomen & functie....................................................................................................................................107
Afwijkingen in Fe huishouding......................................................................................................................107
Tekort........................................................................................................................................................107
Toxiciteit....................................................................................................................................................107
Biologisch belang...........................................................................................................................................107
transferrine................................................................................................................................................107
Zink....................................................................................................................................................................108
Zinktekort......................................................................................................................................................108
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