Test Bank For Applied Pathophysiology for the Advanced Practice Nurse, First EditionLucie Dlugasch, Lachel Story
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Test Bank For Applied Pathophysiology
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Test Bank For Applied Pathophysiology
Test Bank For Applied Pathophysiology for the Advanced
Practice Nurse, First EditionLucie Dlugasch, Lachel Story.Chapter 3 Assessment Quiz
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Test Bank For Applied Pathophysiology for the Advanced
Practice Nurse, First EditionLucie Dlugasch, Lachel Story
Chapter 3 Assessment Quiz
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NAS ISBN13: 9781284182903, add to Ahead, Title tags
Chapter: Chapter 03 - Quiz
Multiple Choice
1. Which of the following coenzymes is(are) necessary for normal red blood cell nuclear maturation and
DNA synthesis pathway?
A) Vitamin D
B) Folate
C) Calcium
D) Vitamin B12 (cobalamin)
E) Both folate and vitamin B12 (cobalamin)
Ans: E
Complexity: Easy
Ahead: Hematopoietic System
Subject: Chapter 3
Title: Hematopoietic Function
2. von Willebrand factor is directly involved in:
A) platelet adhesion and aggregation.
B) platelet production.
C) formation of the fibrin clot.
D) clot dissolution.
Ans: A
Complexity: Easy
Ahead: Hematopoietic System
Subject: Chapter 3
Title: Hematopoietic Function
3. __________ are two important cofactors necessary in the coagulation cascade.
A) Fibrinogen and von Willebrand factor
B) Thromboxane A 2 and calcium
C) Fibrin and thrombin
,Chapter 3 Assessment Quiz
D) Fibrinogen and calcium
Ans: D
Complexity: Easy
Ahead: Hematopoietic System
Subject: Chapter 3
Title: Hematopoietic Function
4. A 50-year-old man is having an acute myocardial infarction and will be administered recombinant
tissue plasminogen activator (t-PA). The medication activates plasminogen in order to:
A) decrease platelet adhesion.
B) increase clotting time.
C) promote fibrinolysis.
D) promote coronary vasodilation.
Ans: C
Complexity: Easy
Ahead: Hematopoietic System
Subject: Chapter 3
Title: Hematopoietic Function
5. A 25-year-old woman comes in complaining of night sweats and at times gets chills. She is losing
weight unintentionally. She has no other complaints. A lymph node in her neck that measures 3 cm and is
painless is palpated. The most likely diagnosis is:
A) non-Hodgkin lymphoma.
B) Hodgkin lymphoma.
C) Burkitt lymphoma.
D) multiple myeloma.
Ans: B
Complexity: Moderate
Ahead: Diseases of the White Blood Cells
Subject: Chapter 3
Title: Hematopoietic Function
6. In Hodgkin lymphoma, B cells can become defective as a result of:
A) T-cell inactivation of B cells.
B) premature apoptosis due to lack of differentiation.
C) errors in immunoglobulin gene arrangements.
D) enhanced conversion into plasma B memory cells.
Ans: C
Complexity: Easy
Ahead: Diseases of the White Blood Cells
Subject: Chapter 3
Title: Hematopoietic Function
7. A 30-year-old man is complaining of cough, difficulty breathing, and fatigue that he has had for about a
month. The cough is nonproductive and he denies fever. He attributes his symptoms to his asthma, which
he had as a child. He borrowed an inhaler like he would use for his asthma but he states it doesn’t seem
to be working. A chest X-ray reveals a mediastinal mass and mediastinal nodes. Based on these findings,
which type of cancer is the most likely diagnosis?
A) Hodgkin lymphoma
,Chapter 3 Assessment Quiz
B) Non-Hodgkin lymphoma
C) Myelodysplastic syndrome
D) Ewing sarcoma
Ans: A
Complexity: Difficult
Ahead: Diseases of the White Blood Cells
Subject: Chapter 3
Title: Hematopoietic Function
8. Which of the following is a characteristic of non-Hodgkin lymphoma in comparison to Hodgkin
lymphoma?
A) It accounts for only 10% of all lymphomas.
B) Reed-Sternberg cells are generally present.
C) Multiple lymph nodes are usually involved.
D) Incidence is higher in young adults.
Ans: C
Complexity: Easy
Ahead: Diseases of the White Blood Cells
Subject: Chapter 3
Title: Hematopoietic Function
9. A mother brings in her 7-year-old son for an evaluation. The mother states her son has not been eating
well. When questioned, the boy states he is not eating because he feels “bumps” in his neck and like his
face is getting big. The mother notes that his face looks different. The family just moved from Africa. The
vital signs are normal and his height and weight are appropriate for his age. Physical exam findings are
unremarkable except for enlarged tonsils and asymmetrical facial bone distortion and nontender,
enlarged lymph nodes palpated in his head and neck region. Based on these findings, which type of
childhood lymphoma is the most likely diagnosis?
A) Burkitt lymphoma
B) Large-cell lymphoma
C) Lymphoblastic lymphoma
D) Hodgkin lymphoma
Ans: A
Complexity: Difficult
Ahead: Diseases of the White Blood Cells
Subject: Chapter 3
Title: Hematopoietic Function
10. Abnormal immunoglobulins known as M proteins and free light chains produced by plasma cells are
characteristic of:
A) non-Hodgkin lymphoma.
B) multiple myeloma.
C) myelodysplastic syndrome.
D) acute myelogenous leukemia.
Ans: B
Complexity: Easy
Ahead: Diseases of the White Blood Cells
Subject: Chapter 3
Title: Hematopoietic Function
, Chapter 3 Assessment Quiz
11. Most lymphomas arise in:
A) T cells.
B) Reed-Sternberg cells.
C) B cells.
D) NK cells.
Ans: C
Complexity: Easy
Ahead: Diseases of the White Blood Cells
Subject: Chapter 3
Title: Hematopoietic Function
12. A 66-year-old black man comes in complaining of back pain. Diagnostic tests are done and include an
X-ray, a complete blood count with differential, and a comprehensive metabolic panel (e.g., glucose,
potassium, calcium, albumin). Which findings are consistent with multiple myeloma?
A) Hypocalcemia
B) High platelet level
C) High neutrophil count
D) Diffuse well-defined “punched out” lytic lesions
Ans: D
Complexity: Moderate
Ahead: Diseases of the White Blood Cells
Subject: Chapter 3
Title: Hematopoietic Function
13. A patient with myelodysplastic syndrome is at risk for the development of which of the following types
of hematologic cancer?
A) Acute myelogenous leukemia
B) Acute lymphocytic leukemia
C) Multiple myeloma
D) Chronic lymphocytic leukemia
Ans: A
Complexity: Easy
Ahead: Diseases of the White Blood Cells
Subject: Chapter 3
Title: Hematopoietic Function
14. Which chromosomal abnormality is commonly associated with chronic myelogenous leukemia?
A) Nondisjunction of chromosome 21
B) Defects in the TP53 tumor suppressor gene
C) Inversion at chromosome 22
D) Translocation of chromosome 9 and 22 leading to a fusion protein known as BCR-ABL
Ans: D
Complexity: Easy
Ahead: Diseases of the White Blood Cells
Subject: Chapter 3
Title: Hematopoietic Function
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