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D115 master set-Advanced Pathophysiology for the Advanced Practice Nurse Exam- Q’s and A’s (Advanced Pathophysiology for the Advanced Practice Nurse)$20.49
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D115 master set-Advanced
Pathophysiology for the Advanced
Practice Nurse Exam- Q’s and A’s
(Advanced Pathophysiology for the
Advanced Practice Nurse)
Which type of genetic disease affects males more frequently than females? -
-Sex-Linked recessive. Since males only have one X and one Y, if the affected
chromosome has the illness, it will be expressed.
-In which two conditions are chromosomal abnormalities the leading known
cause? - -Intellectual disability and fetal miscarriage. Chromosome
abnormalities are the leading known cause of intellectual disability and fetal
miscarriage.
-What are three examples of prenatal diagnostic studies? - -Chorionic villus
sampling (CVS), amniocentesis, and preimplantation genetic testing (PGT)
are examples of prenatal diagnostic studies and are performed in vitro. CVS
is a form of genetic testing that provides genetic information found in utero
and is usually performed between weeks 11 and 14 of pregnancy. An
amniocentesis is a form of genetic testing that evaluates amniotic fluid and
is usually performed during the second trimester, between weeks 15 and 20
of pregnancy. PGT is performed on the embryo prior to implantation.
-Which genetic disorder is characterized by the presence of a zygote having
one chromosome with a normal complement of genes and one chromosome
with a missing gene? - -Cri du chat syndrome (translated as "cry of the cat")
is caused by a DNA deletion. This term describes the cry often heard from a
baby affected by the syndrome. Cri du chat syndrome can present as a
microcephalic, low birth-weight baby with a piercing cry.
-How can an X-linked recessive disease skip generations? - -The disease can
be transmitted through female carriers.
Since females have two copies of the X chromosome, the mother may
provide an unaffected X to a daughter or son. Furthermore, a daughter may
not show signs of the disease because she has the other X (the only X the
father can give to a female) to cancel it out.
-Which type of risk is referred to as the ratio of the disease rate among the
entire population to the disease rate in an unexposed population? - -Relative
risk is a ratio of probability, not an actual occurrence of disease.
, -What are the empirical risks for most multifactorial diseases based on? - -
Many factors from lifestyle to genetics affect multifactorial diseases.
Observation and evaluation of each case individually provides the most
thorough and accurate assessment.
-What refers to the silenced gene of a gene pair. - -The imprinted gene is
the silent gene of a gene pair.
-What is the primary reason that some older adults have impaired
inflammation and wound healing? - -The underlying chronic illness exists.
A generalized inflammatory response seen in chronic illness depletes the
body's reserves to fight against illness.
-Which cells are the body's primary defense against parasite invasion? - -
Eosinophils are the body's primary defense against parasites.
-What Phagocytes bacteria? - -Macrophages work by eating or
phagocytosing bacteria.
-What is the first response to a foreign pathogen? - -Helper T cells
-Which characteristic is the most important determinant of immunogenicity
when considering the antigen? - -Immunogenicity is primarily based on the
ability to recognize something foreign.
-How are erythrocytes destroyed when mismatched blood is administered,
causing an ABO incompatibility? - -The complement pathway is activated in
response to blood incompatibility.
-What is the hypersensitivity reaction that causes atopic dermatitis? - -An
immediate (type I) hypersensitivity reaction causes atopic dermatitis.
-Which four infections are considered fungal infections? - -Infection with a
fungus is called mycosis and includes dermatophytes (e.g., tineas, which
refers to several skin mycoses, including ringworm and athlete's foot) and
yeasts, which include candida and aspergillus.
-When is the earliest after sexual transmission of HIV that lab results can
detect infection? - -Lab testing can detect HIV RNA 4 to 10 days after sexual
transmission, whereas HIV antibody testing may take 23 to 90 days to result
in a positive test. Repeat testing may be needed to rule out a false negative
test due to testing too soon after exposure, especially if a high likelihood of
exposure is suspected.
, -What is a characteristic of exotoxins? - -Exotoxins are released during
bacterial growth.
-Which dietary lifestyle choice has been associated with a decreased risk for
developing colon cancer? - -The results of decreased fat consumption have
been widely studied and have demonstrated a decreased risk of developing
colon cancer.
-Which cancer is an individual who has worked with asbestos for over 40
years most likely to develop? - -Asbestos exposure results in an increased
risk of lung and lung lining cancer.
-Which statement is true regarding ultraviolet (UV) light?
The degree of damage is not affected by the light's wavelength. - -UV light
causes basal cell carcinoma and squamous cell carcinoma when the UVB
rays hit DNA strands, causing thymine base pairs that are side by side to pair
together, becoming thymine dimers. These thymine dimers lead to cell death
or cancer.
-Which cancer does exercise have a convincing impact on reducing? - -
Exercise-induced myokines cause apoptosis of colon cancer cells.
-Low healthcare literacy is recognized as a major risk factor in blood
pressure control and has been shown to have adverse effects on health
outcomes.
true or false - -TRUE
By providing patient education at the appropriate literacy level, improved
health outcomes may result.
-One of the goals of the National Action Plan to Improve Health Literacy is to
incorporate research and evidence-based plans of treatment from childhood
through university-level education in a manner consistent with an
individual's literacy level.
True or false - -True
Ensuring the individual can understand all elements of a treatment plan is
crucial for understanding and compliance.
-What is a red flag for low healthcare literacy? - -Low literacy often leads to
perceived noncompliance to medical instructions, including medication
instructions. Ensuring the patient fully understands all instructions is critical
for understanding.
-Amniocentesis is recommended for pregnant women with certain health
histories.
Which health history would result in an amniocentesis recommendation? - -
Those who have a family history of genetic disorders
, -Studies have identified several genes that play a role in the prevention of
obesity.
What do these genes influence? - -Regulation of appetite-Research has
shown that genetic mutations may cause alterations in the regulation of
appetite.
-Which concept is data reporting that sickle cell disease affects
approximately 1 in 600 black Americans an example of? - -Prevalence tells
us how often disease is seen in a population, which includes all people with
the disease at a given time, at any stage in the disease progression.
-What describes a chromosomal defect caused by Prader-Willi syndrome? - -
Prader-Willi syndrome is caused by a disorder of a portion of chromosome
15. Normally, a portion of this chromosome is inherited from both parents.
With Prader-Willi syndrome, the chromosome inherited from the father is
problematic.
-Which action is a purpose of the inflammatory process? - -Prevent infection
of the injured tissue
The inflammatory response is a defense mechanism designed to remove
damaged tissue so the body can heal.
-Which leukocytes are elevated in response to acute inflammatory reactions
when considering white blood cell differentials?
Monocytes
Neutrophils
Basophils
Eosinophils - -Neutrophils are one of the first responders to acute
inflammation, and an increase in neutrophils demonstrates an acute
inflammatory response.
-Which type of immunity is produced by an individual after either natural
exposure to the antigen or after immunization against the antigen? - -Active-
acquired immunity or naturally acquired active immunity occurs when an
individual is exposed to a live pathogen and develops the disease or
becomes immune as a result of a vaccine.
-Which characteristics do atopic individuals have that make them
genetically predisposed to develop allergies? - -The greater quantities of IgE
in atopic individuals make them genetically predisposed to develop allergies.
IgE mediates the immune response to allergens; therefore, the more IgE one
has, the stronger the response can be to an allergen. Think of it as having
more soldiers in the army to fight the war.
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