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WGU D027 Practice Test Questions and Answers
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WGU D027 Practice Test Questions andAnswers
A patient has endured several dosage adjustments of his tricyclic
antidepressant, so the provider recommends genetic testing. Which
statement correctly describes the rationale for genetic testing?
a. The CYP2D6 gene influences metabolism of tricyclic antidepressants and
certain other drugs.
b. The HER2 gene is a tumor marker that impacts metabolism of tricyclic
antidepressants.
c. The BRCA2 gene influences metabolism of certain drugs and increases the
risk for breast cancer.
d. The x linked OPN1MW gene for male color blindness also slows
metabolism of certain - -a. The CYP2D6 gene influences metabolism of
tricyclic antidepressants and certain other drugs.
HER2 is a gene often implicated with cancer, as is BRCA2. OPN1MW is the
gene that codes for color blindness in men. Metabolism of 25% of all
prescribed drugs, including tricyclic antidepressants, beta adrenergic
receptor blockers, and neuroleptics, is influenced by variants in a certain
gene, requiring genetic testing to reduce trial-and-error in estimating
appropriate drug-dosage levels.
-According to the Centers for Disease Control and Prevention, the 10 most
costly chronic conditions include cardiovascular diseases, obesity, asthma,
diabetes, smoking and alcohol related conditions, cancer, Alzheimer's
disease, arthritis and stroke. Which are the top 4 in ranking from most costly
to least costly?
a. Cardiovascular diseases, obesity, diabetes, cancer
b. Cardiovascular diseases, diabetes, obesity, cancer
c. Cardiovascular diseases, Smoking-related conditions, Alcohol-related
conditions, diabetes
d. Cardiovascular diseases, Stroke, Obesity, Diabetes - -c. Cardiovascular
diseases, Smoking-related conditions, Alcohol-related conditions, diabetes
-A mother brought her child to the doctor for genetic testing. The health
care provider was trying to explain the genetic results of the child. During his
explanation he tells the mother that the child has 2 X chromosomes and a Y
chromosome in each cell. He begins to explain some physical appearances
the mother might notice on her son. He explains that she might notice that
he has sparse body hair, long limbs and small testes. The health care
practitioner is explaining which syndrome to the mother.
, a. Klinefelter syndrome
b. Turners' syndrome
c. Down syndrome
d. Kawasaki's disease - -a. Klinefelter syndrome
Klinefelter syndrome is an individual with at least 2 X chromosomes and a Y
chromosome in each cell. Because of the Y chromosome these individuals
have a male appearance, but they are usually sterile and about half develop
female-like breasts.
-A patient reports a maternal family history of Lynch syndrome. Which
laboratory finding might indicate a need for further testing for the presence
of Lynch syndrome in this patient?
a. Elevated thyroid-stimulating hormone
b. Low cortisol level
c. Positive heme-occult test
d. Sputum positive for Pseudomonas Aeruginosa - -a. Positive heme-occult
test
Positive heme-occult because Lynch syndrome is a hereditary form of
colorectal cancer and colorectal bleeding can be a sign of cancer
-An individual's acquired immunity is dependent on the function of which
cells? (Select all that apply.)
a. B lymphocytes
b. Opsonins
c. T lymphocytes
d. Macrophages - -a. B lymphocytes
c. T lymphocytes
d. Macrophages
T lymphocytes, B lymphocytes, macrophages, and dendritic cells are
involved in acquired immunity.
-A 17-year-old female comes to the clinic for a physical exam. As part of the
visit, the APRN considers her risk factors for type 2 diabetes mellitus (T2DM).
Risk factors for T2DM would likely include all of the following except:
a. Native American ancestry
b. Family history of type 1 diabetes mellitus (T1DM)
c. Obesity
d. Personal history of polycystic ovary syndrome (PCOS) - -b. Family history
of type 1 diabetes mellitus (T1DM)
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