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BLOOD BANK MIDTERM EXAM.2023 complete questions with answers
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BLOOD BANK MIDTERM EXAM (3/13/2021)c - ANSWERThe term "Rh positive" refers to the presence of which of the following:
a. E
b. B
c. D
d. C
e. None of the above
e - ANSWERWhich of the following is TRUE with ABO blood group dyscrepancies?
a.Group I: excess amounts of blood group-specific soluble (BGSS) substances present in the plasma in association with certain diseases, such as carcinoma of the stomach and pancreas
b.NOTA
c.Group I, II, IV: Leukemia
d.Group II,III: Waldenstroms macroglublinemia
e.Two of the choices are correct
a - ANSWERThe principle of the K-B test is resistance
a.of fetal hemoglobin to acid solutions
b.of fetal hemoglobin to alkaline solutions
c.adult hemoglobin to alkaline solutions
d.adult hemoglobin to acid solutions
c - ANSWERA cord blood work up was ordered on Baby Boy Lim. The mother who is Mrs. Lim is O-negative. Results on the baby are as follows:
ANTI A = 4+
ANTI B = 0
ANTI A,B =4+
ANTI D =0
DAT = 2+
The test for weak D was positive at AHG. Is the mother an RhIg candidate?
a.Yes, the mother is Rh negative
b.No, the baby is Rh positive
c.Yes, the baby's Rh type cannot be determined due to a positive DAT
d.Ask the father for confirmation and repeat Rh typing, DAT
c - ANSWERWhat reaction would be the same for an A1 and A2 individuals? a.Positive reaction with Dolichos biflorus
b.Equal reaction with Ulex europaeus
c.Positive reaction with Anti-A, B
d. Positive reaction with A1 cells
e.AOTA
c - ANSWERWhat test should be performed on blood that will be transfused to an acidotic or hypoxic infant?
a. CMV
b. EBV
c. Hgb S
d. All are correct
I,II,III - ANSWERWhich of the following is TRUE?
I. Anti-S and anti-s are IgG antibodies, reactive at 37'C and the antiglobulin phase; they may bind complement and have been associated with HDN and hemolytic transfusion reactions
II. Pathogenic anti-I is typically a strong cold autoagglutinin that demonstrates high titer reactivity at 4C and reacts over a wide thermal range (up to 30'-32'C).
III. The Kell blood group antigens are destroyed by DTT, ZZAP, and glycine-acid-EDTA.
I - ANSWERWhich of the following is TRUE ?
I. Kidd system antibodies are a common cause of delayed hemolytic transfusion reactions
II. Anti-Lub is an IgM antibody reactive at the AHG phase
III. Lua and Lub are antigens produced by allelic codominant genes; they are well developed at birt
d - ANSWERFalse negative reactions in routine Rh typing may result from:
a. Overly vigorous resuspension after centrifugation. Shaking too hard results in dispersal of weak agglutination. Careful resuspension is essential.
b. Reagent deterioration. Prolonged or incorrect storage of reagents may result in the destruction of the antibody in the reagent. Antiserum should not be used after the expiration date.
c. Use of the wrong antiserum. Careful reading of labels on each reagent vial is required. Antiserum labels must not be obscured, and those with unreadable labels should be discarded.
d. A and B
e. B and C
I antigen - ANSWERA patient with an M. pneumoniae infection will most likely develop a
cold autoantibody with specificity to which antigen?
c - ANSWERPatient K: RBC Phenotype: ABH Le(a-b+)What is/are the antibodies present in his/her plasma?
a. Anti H b. Anti Lea and Anti Leb
c. NOTA
d - ANSWERWhich blood typing results are most likely to occur when a patient has a colorectal cancer and or infected with E.coli 086?
a.
ANTI-A 4+
ANTI-B 4+
A cells -
B cells -
b.
ANTI-A 4+
ANTI-B 4+
A cells -
B cells 3+
c.
ANTI-A 4+
ANTI-B -
A cells 1+
B cells 4+
d.
ANTI-A 4+
ANTI-B 2+
A cells - B cells 4+
e.
ANTI-A 4+
ANTI-B 2+
A cells 2+
B cells 2+
d - ANSWERWhich of the following is TRUE?
a. Immunoglobulins are the product of plasma cell protein production, and these protein-
carbohydrate moieties (glycoprotein) bind to their antigens in a highly specific fashion.
b. Each immunoglobulin molecule may be thought of as consisting of two identical polypeptide heavy chains (H) and two identical polypeptide light chains (L)
c.The hinge region of the antibody molecule between the CH2 and CH3 domains is the area that provides flexibility in allowing the molecule to combine with antigen
d. Two of the choices are correct
e. AOTA
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