TEST BANK ROSENTHAL LEHNE'S PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE PROVIDERS 1ST EDITIONTable of Contents
Chapter 1: Prescriptive Authority .......................................................................................................................................... 3 Chapter 2: Ra...
Chapter 1: Prescriptive Authority .......................................................................................................................................... 3
Chapter 2: Rational Drug Selection and Prescription Writing .......................................................................................... 5
Chapter 3: Promoting Positive Outcomes of Drug Therapy............................................................................................. 7
Chapter 4: Pharmacokinetics, Pharmacodynamics, and Drug Interactions ..................................................................10
Chapter 5: Adverse Drug Reactions and Medication Errors ...........................................................................................14
Chapter 6: Individual Variation in Drug Responses .........................................................................................................19
Chapter 7: Drug Therapy During Pregnancy and Breast-Feeding ..................................................................................22
Chapter 8: Drug Therapy in Pediatric Patients ..................................................................................................................26
Chapter 9: Drug Therapy in Geriatric Patients ..................................................................................................................30
Chapter 10: Basic Principles of Neuropharmacology .......................................................................................................34
Chapter 11: Physiology of the Peripheral Nervous System .............................................................................................37
Chapter 12: Muscarinic Agonists and Antagonists ...........................................................................................................40
Chapter 13: Adrenergic Agonists .........................................................................................................................................43
Chapter 14: Adrenergic Antagonists ...................................................................................................................................47
Chapter 15: Indirect-Acting Antiadrenergic Agents .........................................................................................................52
Chapter 16: Introduction to Central Nervous System Pharmacology ...........................................................................56
Chapter 17: Drugs for Parkinson's Disease ........................................................................................................................58
Chapter 18: Drugs for Alzheimer's Disease .......................................................................................................................62
Chapter 19: Drugs for Epilepsy............................................................................................................................................65
Chapter 20: Drugs for Muscle Spasm and Spasticity ........................................................................................................68
Chapter 21: Local Anesthetics ..............................................................................................................................................72
Chapter 22: Opioid Analgesics, Opioid Antagonists, and Nonopioid Centrally Acting Analgesics ........................75
Chapter 23: Drugs for Headache .........................................................................................................................................80
Chapter 24: Antipsychotic Agents and Their Use in Schizophrenia ..............................................................................85
Chapter 25: Antidepressants .................................................................................................................................................90
Chapter 26: Drugs for Bipolar Disorder.............................................................................................................................93
Chapter 27: Sedative-Hypnotic Drugs ................................................................................................................................98
Chapter 28: Management of Anxiety Disorders ............................................................................................................. 100
Chapter 29: Central Nervous System Stimulants and Attention-Deficit/HyperactivityDisorder ..................... 104
Chapter 30: Drug Abuse I: Basic Considerations .......................................................................................................... 108
Chapter 31: Drug Abuse II: Alcohol ................................................................................................................................ 110
Chapter 32: Drug Abuse III: Nicotine and Smoking .................................................................................................... 114
Chapter 33: Drug Abuse IV: Major Drugs of Abuse Other Than Alcohol and Nicotine ...................................... 118
Chapter 34: Review of Hemodynamics............................................................................................................................ 124
Chapter 35: Diuretics .......................................................................................................................................................... 126
Chapter 36: Drugs Acting on the Renin-Angiotensin-Aldosterone System ............................................................... 130
Chapter 37: Calcium Channel Blockers ........................................................................................................................... 134
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,Chapter 38: Vasodilators .................................................................................................................................................... 136
Chapter 39: Drugs for Hypertension ................................................................................................................................ 140
Chapter 40: Drugs for Heart Failure ................................................................................................................................ 146
Chapter 41: Antidysrhythmic Drugs ................................................................................................................................. 153
Chapter 42: Prophylaxis of Atherosclerotic Cardiovascular Disease: Drugs That Help Normalize Cholesterol and
Triglyceride Levels............................................................................................................................................................... 159
Chapter 43: Drugs for Angina Pectoris............................................................................................................................ 165
Chapter 44: Anticoagulant, Antiplatelet, and Thrombolytic Drugs ............................................................................. 171
Chapter 45: Drugs for Deficiency Anemias .................................................................................................................... 177
Chapter 46: Drugs for Diabetes Mellitus ......................................................................................................................... 182
Chapter 47: Drugs for Thyroid Disorders ....................................................................................................................... 187
Chapter 48: Estrogens and Progestins: Basic Pharmacology and Noncontraceptive Applications....................... 192
Chapter 49: Birth Control .................................................................................................................................................. 194
Chapter 50: Androgens ....................................................................................................................................................... 199
Chapter 51: Drugs for Erectile Dysfunction and Benign Prostatic Hyperplasia ....................................................... 203
Chapter 52: Review of the Immune System.................................................................................................................... 205
Chapter 53: Childhood Immunization ............................................................................................................................. 208
Chapter 54: Antihistamines................................................................................................................................................ 213
Chapter 55: Cyclooxygenase Inhibitors: Nonsteroidal Anti-inflammatory Drugs andAcetaminophen ......... 217
Chapter 56: Glucocorticoids in Nonendocrine Disorders ............................................................................................ 221
Chapter 57: Drug Therapy of Rheumatoid Arthritis ..................................................................................................... 226
Chapter 58: Drug Therapy of Gout .................................................................................................................................. 229
Chapter 59: Drugs Affecting Calcium Levels and Bone Mineralization ..................................................................... 232
Chapter 60: Drugs for Asthma and Chronic Obstructive Pulmonary Disease .......................................................... 237
Chapter 61: Drugs for Allergic Rhinitis, Cough, and Colds ......................................................................................... 243
Chapter 62: Drugs for Peptic Ulcer Disease ................................................................................................................... 248
Chapter 63: Laxatives.......................................................................................................................................................... 252
Chapter 64: Other Gastrointestinal Drugs ...................................................................................................................... 256
Chapter 65: Vitamins .......................................................................................................................................................... 262
Chapter 66: Drugs for Weight Loss.................................................................................................................................. 266
Chapter 67: Complementary and Alternative Therapies ............................................................................................... 270
Chapter 68: Basic Principles of Antimicrobial Therapy ................................................................................................ 273
Chapter 69: Drugs That Weaken the Bacterial Cell Wall I: Penicillins ....................................................................... 277
Chapter 70: Drugs That Weaken the Bacterial Cell Wall II: Other Drugs ................................................................. 281
Chapter 71: Bacteriostatic Inhibitors of Protein Synthesis ........................................................................................... 285
Chapter 72: Aminoglycosides: Bactericidal Inhibitors of Protein Synthesis .............................................................. 291
Chapter 73: Sulfonamides and Trimethoprim ................................................................................................................ 296
Chapter 74: Drug Therapy of Urinary Tract Infections ................................................................................................ 300
Chapter 75: Antimycobacterial Agents............................................................................................................................. 305
Chapter 76: Miscellaneous Antibacterial Drugs .............................................................................................................. 311
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,Chapter 77: Antifungal Agents .......................................................................................................................................... 313
Chapter 78: Antiviral Agents I: Drugs for Non-HIV Viral Infections ....................................................................... 320
Chapter 79: Antiviral Agents II: Drugs for HIV Infection and Related OpportunisticInfections ........................ 325
Chapter 80: Drug Therapy of Sexually Transmitted Diseases ...................................................................................... 329
Chapter 81: Anthelmintics, Antiprotozoal Drugs, and Ectoparasiticides ................................................................... 332
Chapter 82: Supportive Care of Patients Receiving Anticancer Drugs ....................................................................... 335
Chapter 83: Drugs for Cancer Pain .................................................................................................................................. 339
Chapter 84: Drugs for the Eye .......................................................................................................................................... 345
Chapter 85: Drugs for the Skin ......................................................................................................................................... 348
Chapter 86: Drugs for the Ear........................................................................................................................................... 355
Chapter 87: Agents Affecting the Volume and Ion Content of Body Fluids ............................................................ 359
Chapter 88: Management of ST-Elevation Myocardial Infarction .............................................................................. 363
Chapter 89: Additional Acute Care Drugs....................................................................................................................... 366
Chapter 1: Prescriptive Authority
Multiple Choice
1. An APRN works in a urology clinic under the supervision of a physician who does not restrictthe types of
medications the APRN is allowed to prescribe. State law does not require the APRN to practice under
physician supervision. How would the APRN’s prescriptive authoritybe described?
a. Full authority
b. Independent
c. Without limitation
d. Limited authority
ANS: B
The APRN has independent prescriptive authority because the regulating body does not require that the
APRN work under physician supervision. Full prescriptive authority gives the provider the right to prescribe
independently and without limitation. Limited authority places restrictions on the types of drugs that can be
prescribed.DIF: Cognitive Level: ComprehensionREF: p. 1TOP: Nursing Process: I MSC: NCLEX Client
Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
2. Which factors increase the need for APRNs to have full prescriptive authority?
a. More patients will have access to health care.
b. Enrollment in medical schools is predicted to decrease.
c. Physician’s assistants are being utilized less often.
d. APRN education is more complex than education for physicians.
ANS: A
Implementation of the Affordable Care Act has increased the number of individuals with health care
coverage, and thus the number who have access to health care services. The increase in the number of
patients creates the need for more providers with prescriptive authority. APRNs can fill this practice gap.DIF:
Cognitive Level: ComprehensionREF: p. 2TOP: Nursing Process: Implementation MSC: NCLEX Client
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, Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
3. Which factors could be attributed to limited prescriptive authority for APRNs?Select all
that apply.
a. Inaccessibility of patient care
b. Higher health care costs
c. Higher quality medical treatment
d. Improved collaborative care
e. Enhanced health literacy
ANS: A , B
Limiting prescriptive authority for APRNs can create barriers to quality, affordable, and accessible patient care.
It may also lead to poor collaboration among providers and higher health care costs. It would not directly
impact patient’s health literacy.DIF: Cognitive Level: ComprehensionREF:
p. 2TOP: Nursing Process: Implementation MSC: NCLEX Client Needs Category: Physiologic Integrity:
Pharmacologic and Parenteral Therapies
4. Which aspects support the APRN’s provision for full prescriptive authority?Select all
that apply.
a. Clinical education includes prescription of medications and disease processes.
b. Federal regulations support the provision of full authority for APRNs.
c. National examinations provide validation of the APRN’s ability to provide safe care.
d. Licensure ensures compliance with health care and safety standards.
e. Limiting provision can decrease health care affordability.
ANS: A , C , D
APRNs are educated to practice and prescribe independently without supervision. National examinations
validate the ability to provide safe and competent care. Licensure ensures compliance with standards to
promote public health and safety. Limited prescriptive authority creates numerous barriers to quality,
affordable, and accessible patient care.DIF: Cognitive Level: ComprehensionREF: pp. 1-2TOP: Nursing
Process: Implementation MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and
Parenteral Therapies
5. Which aspects support the APRN’s provision for full prescriptive authority?Select all
that apply.
a. Clinical education includes prescription of medications and disease processes.
b. Federal regulations support the provision of full authority for APRNs.
c. National examinations provide validation of the APRN’s ability to provide safe care.
d. Licensure ensures compliance with health care and safety standards.
ANS: A , C , D
APRNs are educated to practice and prescribe independently without supervision. National examinations
validate the ability to provide safe and competent care. Licensure ensures compliance with standards to
promote public health and safety. Limited prescriptive authority creates numerous barriers to quality,
affordable, and accessible patient care.DIF: Cognitive Level:
ComprehensionREF: pp. 1-2TOP: Nursing Process: Implementation MSC: NCLEX Client Needs Category:
Physiologic Integrity: Pharmacologic and Parenteral Therapies
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