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Test Bank - Berne and Levy Physiology, 7th Edition (Koeppen, 2018), Chapter 1-44 | All Chapters
Test Bank - Berne and Levy Physiology, 7th Edition (Koeppen, 2018), Chapter 1-44 | All Chapters
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TEST BANKBerne & Levy Physiology
Bruce M. Koeppen and, Bruce A. Stanton
7th Edition Table of Contents
Chapter 01 Principles of Cell Function 1
Chapter 02 Homeostasis of Body Fluids 6
Chapter 03 Signal Transduction, Membrane Receptors, Second Messengers, and Regulation of Gene Expression 8
Chapter 04 The Nervous System-Introduction to Cells and Systems 10
Chapter 05 Generation and Conduction of Action Potentials 12
Chapter 06 Synaptic Transmission 15
Chapter 07 The Somatosensory System 18
Chapter 08 The Special Senses 21
Chapter 09 Organization of Motor Function 24
Chapter 10 Higher Functions of the Nervous System 27
Chapter 11 The Autonomic Nervous System and Its Central Control 30
Chapter 12 Skeletal Muscle Physiology 33
Chapter 13 Cardiac Muscle 36
Chapter 14 Smooth Muscle 39
Chapter 15 Overview of Circulation 42
Chapter 16 Elements of Cardiac Function 43
Chapter 17 Properties of the Vasculature 48
Chapter 18 Regulation of the Heart and Vasculature 50
Chapter 19 Integrated Control of the Cardiovascular System 52
Chapter 20 Structure and Function of the Respiratory System 56
Chapter 21 Static Lung and Chest Wall Mechanics 60
Chapter 22 Dynamic Lung and Chest Wall Mechanics 63
Chapter 23 Ventilation, Perfusion, and Relationships 66
Chapter 24 Oxygen and Carbon Dioxide Transport 69
Chapter 25 Control of Respiration 72
Chapter 26 Non-Physiologic Functions of the Lung-Host Defense and Metabolism 75
Chapter 27 Functional Anatomy and General Principles of Regulation in the Gastrointestinal Tract 78
Chapter 28 The Cephalic, Oral, and Esophageal Phases of the Integrated Response to a Meal 80
Chapter 29 The Gastric Phase of the Integrated Response to a Meal 82
Chapter 30 The Small Intestinal Phase of the Integrated Response to a Meal 84
Chapter 31 The Colonic Phase of the Integrated Response to a Meal 86
Chapter 32 Transport and Metabolic Functions of the Liver 88
Chapter 33 Elements of Renal Function 90
Chapter 34 Solute and Water Transport along the Nephron-Tubular Function 94
Chapter 35 Control of Body Fluid Osmolality and Volume 98
Chapter 36 Potassium, Calcium, and Phosphate Homeostasis 102
Chapter 37 Role of the Kidneys in the Regulation of Acid-Base Balance 105
Chapter 38 Introduction to the Endocrine System 108 Chapter 39 Hormonal Regulation of Energy Metabolism 111
Chapter 40 Hormonal Regulation of Calcium and Phosphate Metabolism 116
Chapter 41 The Hypothalamus and Pituitary Gland 119
Chapter 42 The Thyroid Gland 122
Chapter 43 The Adrenal Glands 126
Chapter 44 The Male and Female Reproductive Systems 130 Koeppen: Berne and Levy Physiology, 7th Edition Chapter 01: Principles of Cell Function Test Bank Multiple Choice 1. The subcellular structure that degrades proteins is called the: A. Tight junction B. Mitochondria C. Lysosome D. Plasma membrane E. Ribosome ANS: C 2. An experiment is done to measure the uptake of an a mino acid into a cell. The following data are obtained: If Na+ is removed from the extracellular bathing solution , or if a drug is added that prevents the cell from making adenosine triphosphat e (ATP), the uptake of amino acid into the cell is markedly reduced. According to thi s information, which of the following mechanisms is probably responsible for the transpor t of the amino acid into the cell? A. Passive diffusion through the lipid bilayer B. Uniporter C. Transport ATPase D. Na+ symporter E. Na+ antiporter ANS: D 3. A membrane permeable by only Na+ separates two compartments containing Na 2SO 4, shown as follows: ______________________________________________________________________________________________
______________________________________________________________________________________________Test Bank - Berne and Levy Physiology, 7th Edition (Koeppen, 2018)
1 | P a g e Test Bank 1-2 Electrodes are placed in both compartments, and a v oltage is applied (that of compartment A is held at 0 mV). What voltage applie d to compartment B would result in no net movement of Na+ across the membrane separating the compartments? A. –60 mV B. –30 mV C. 0 mV D. +30 mV E. +60 mV ANS: E 4. The resting membrane potential of a cell is –85 mV. The intracellular and extracellular concentrations of several ions are indicated in the following table, as is the calculated Nernst equilibrium potential (E i) for each of these ions: Ion Concentration Inside Cell Concentration Outside Cell Ei Na+ 12 mEq/L 145 mEq/L 66 mV K+ 150 mEq/L 4 mEq/L –96 mV Cl– 30 mEq/L 105 mEq/L –33 mV Ca++ 0.0001 mmol/dL 1 mmol/dL 122 mV The membrane has channels for Na+, K+, Cl–, and Ca++. The conductance of the membrane is the greatest for which ion? A. Na+ B. K+ C. Cl– D. Ca++ ANS: B 5. A cell contains the following membrane transporters : ______________________________________________________________________________________________
______________________________________________________________________________________________Test Bank - Berne and Levy Physiology, 7th Edition (Koeppen, 2018)
2 | P a g e Test Bank 1-3 Na+ channel K+ channel Na+,K+-ATPase The resting membrane voltage of the cell is –80 mV, and the intracellular and extracellular ion concentrations are as follows: Ion Intracellular Concentration Extracellular Concentration Na+ 10 mEq/L 145 mEq/L K+ 120 mEq/L 4 mEq/L The cell is treated with a drug to inhibit the Na+,K+-ATPase. What would be the effect of this drug on the following parameters? Intracellular [Na+] Intracellular [K+] Cell Volume Membrane Voltage A. Decrease Decrease Decrease Depolarize B. Increase Decrease Increase Depolarize C. Increase Increase Increase No change D. Decrease Increase Decrease Hyperpolarize E. Increase Increase Decrease Hyperpolarize ANS: B 6. Which of the labeled proteins (shaded) is attached to the membrane by a glycosylphosphatidylinositol (GPI) anchor? ANS: E 7. A cell has channels for Na+, K+, and Cl– in its plasma membrane. The resting membrane potential is –60 mV (cell interior negative). The i ntracellular and extracellular concentrations for these ions, as well as the calcu lated Nernst potentials, are listed as follows: ______________________________________________________________________________________________
______________________________________________________________________________________________Test Bank - Berne and Levy Physiology, 7th Edition (Koeppen, 2018)
3 | P a g e Test Bank 1-4 Ion Intracellular Concentration Extracellular Concentration Ei Na+ 14 mEq/L 140 mEq/L 60 mV K+ 150 mEq/L 5 mEq/L –89 mV Cl– 10 mEq/L 100 mEq/L –60 mV A drug is applied to the cell that increases the pe rmeability of the cell by Cl– (i.e., it opens Cl– channels). What effect will this drug have on the net movement of Cl– across the plasma membrane? A. Net Cl– movement out of the cell will be increased. B. Net Cl– movement into the cell will be increased. C. There will be no change in the net movement of Cl–. ANS: C 8. Reducing the extracellular [K+] would be expected to have which of the following effects on the resting membrane potential and on th e excitability of ventricular myocytes? Membrane Potential Excitability A. Unchanged Unchanged B. Hyperpolarized Decreased C. Hyperpolarized Increased D. Depolarized Decreased E. Depolarized Increased ANS: B 9. A cell is bathed in an isotonic NaCl solution that contains 5 mmol/L of glucose. The intracellular concentration of glucose is 10 mmol/L . What is the most likely mechanism for the transport of glucose across the plasma memb rane into this cell? A. Glucose uniporter B. Na+-glucose symporter C. Na+-glucose antiporter D. Diffusion of glucose through the lipid bilayer of t he membrane ANS: B 10. A blood sample is taken from an individual whose bl ood osmolality is 295 mOsm per kilogram of water. Red blood cells from this sample are then placed in the following solutions: ______________________________________________________________________________________________
______________________________________________________________________________________________Test Bank - Berne and Levy Physiology, 7th Edition (Koeppen, 2018)
4 | P a g e Test Bank 1-5 Solution Osmolality (mOsm/kg H2O) Reflection Coefficient ( of Solute 1. NaCl 300 1 2. Fructose 300 0.5 3. Urea 300 0 4. CaCl 2 100 1 5. KCl 150 1 The red blood cells in which of these solutions wil l swell to the greatest degree? A. 1 B. 2 C. 3 D. 4 E. 5 ANS: C 11. A solution that causes a cell to shrink is: A. Isotonic B. Hypotonic C. Hypertonic ANS: C 12. Osmosis is: A. The active transport of water B. The number of solute particles in 1 kg of water C. The diffusion of water across cell membranes D. The defined as the weight of a volume of a solution divided by the weight of an equivalent volume of distilled water E. The amount of a substance relative to its molecular weight ANS: C ______________________________________________________________________________________________
______________________________________________________________________________________________Test Bank - Berne and Levy Physiology, 7th Edition (Koeppen, 2018)
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