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NR 293 - Exam 1 question well explained, 2023/2024.

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Pharmaceutics – answers the dosage form that determines the rate of drug dissolution Pharmacodynamics - answers- what the drug does to the body - Therapeutic effects Selective Enzyme Interaction – answers when the drug binds to an enzyme molecule and inhibits (blocks) or stimulates the e...

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  • December 22, 2023
  • 12
  • 2023/2024
  • Exam (elaborations)
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NR 293 - Exam 1 question well explained,
2023/2024.

Pharmaceutics – answers the dosage form that determines the rate of drug dissolution



Pharmacodynamics - answers- what the drug does to the body

- Therapeutic effects



Selective Enzyme Interaction – answers when the drug binds to an enzyme molecule and inhibits
(blocks) or stimulates the enzyme action with the normal target cell



Pharmacokinetics - answers- what the body does to the drug

- Study of movement of drugs throughout the body



Absorption – answers being absorbed or used by the tissues



Fastest to Slowest Absorption Routes by Mouth - answers- Sublingual

- Liquid Suspension

- Capsule

- Tablet

- Enteric Coated Tablet

- Extended Release Tablet



First Pass Effect – answers oral doses of drugs are absorbed into the GI tract and metabolized by the
liver, resulting in a reduced amount of bioavailability or active drug in the circulatory system.

*Oral doses are generally higher to allow for this effect*



Drugs that are effected by First Pass Effect - answers- Elixir

, - Tablets

- Capsules

*enteral drugs*



What drugs aren't effected by First Pass Effect? - answers- IV

- Sublingual

- Transdermal Patch

- Suppository

*parenteral drugs*



Half Life - answers- the time it takes for 1/2 of the drug dose to be eliminated from the body

-drugs with a long half-life enables them to be taken less frequently



EX: ibuprofen has a half-life of 2 hours, after 1 half-life 200 mg will turn into 100 mg



Plasma - answers yellow fluid part of blood that holds the cells



Interstitial Fluid - answers fluid within the cells



Transcellular Fluid - answers part of extracellular fluid



Areas of Fast Distribution - answers- Heart

- Liver



Areas of Slow Distribution - answers- Muscle

- Fat

- Skin

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