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Summary unipolar depression explanations & treatments

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unipolar depression features & symptoms, biological and psychological explanations & treaments summary and evaluation key words highlighted for better recall

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  • January 1, 2024
  • 15
  • 2023/2024
  • Summary
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Scanning techniques more objective: show blocking glutamate relates to psychotic
symptoms

Humans undergoing scanning respond differently

Focus on too many factors: hard to come to single conclusion

Ethics

Some animal studies unethical but accepted at the time

Advantage

Aim of helping to develop more effective treatments for SZ beneficial for patients for
whom current antipsychotics are ineffective

Large % don’t respond quickly to current medications = while to develop effective
treatment regimen

Newer drug compounds provide answer by working on levels of other neurotransmitters




UNIPOLAR DEPRESSION
● Mood disorder
● Non-psychotic : understands difference btw imagination + reality
● Recognises own mood is irrational / inappropriate but can’t help feeling that way

Not single disorder but has subtypes classified by severity, length + psychotic / other
features

FEATURES (types, statistics, people affected)

● 3.5 million in UK

More prevalent in

● women (12%) than men (8%) - lifetime rate
● 27% of divorced or separated, compared to 20% of single & 16% in
stable relationships
● lower-income households

, 53

● 50-54 age group

mL in young adulthood

Course of disorder varies in its severity: some function well + go in remission within
few months of onset and remain symptom-free

Personality disorders + high anxiety have long-lasting severe symptoms with few
periods of remission

E.g. substance misuse, borderline personality disorders (instability in interpersonal
relationships & self-image, impulsivity), anxiety, panic disorder, OCD, anorexia
nervosa + bulimia

Risk of developing major depression is affected by temperament:

Neuroticism (emotional instability e.g. fear, anxiety, envy) is risk factor combined
with stressful life events + 1st degree relative with disorder

High mortality + affects course of other illnesses:
suicide higher in male sufferers but attempted more frequently by females

mL: lives alone, single + strong feelings of hopelessness

High prevalence rate but varies across cultures due to cultural differences in
diagnosis & reporting of depression rather than simple link btw culture + disorder

DSM estimates rate at 7% USA but higher in females aged 18-29 outnumbering
males by 2:1 ratio

TYPES :

MILD : limited negative effect on daily life

MAJOR: interferes with daily life

POST-NATAL / PARTUM: overwhelmed with panic attacks (2-3 weeks after
birth)

Seasonal Affective Disorder (SAD): interfere with moods and with sleeping
and eating patterns all winter

Lasts for several months but usual to recover & relapse

SYMPTOMS (bhvs, thoughts) intense + last for long time

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