Hematology ASCP exam

Bone marrow and Peripheral blood - Answer- Growth factors that stimulate cell line maturation are: Locations of active marrow in adults - Answer- Flat bones What conditions are associated with increased storage of iron - Answer- Hemosiderosis Hemochromatosis Transferrin - Answer- iron transport protein Iron storage forms: - Answer- ferritin and hemosiderin Porphyrias - Answer- diseases that result from deficiencies of any of several enzymes required to make heme Heme precursor orders Memory: *DELTA, POUR YOUR COP PROTO* a cup of *HEME* - Answer- Delta-amniolevolini acid breaks down into Porphobilinogen breaks down into Uroporphyrinogen breaks down into Coproporphyrinogen breaks down into Protoporphyrin breaks down into Heme + Globin hemoglobin-oxygen dissociation curve Memory: Shift Right wont hold tight, Shift left No wont let go - Answer- Shift to the left- O2 NOT released to tissue adequately Shift to the right- O2 released to tissue more easily Left Shift - Answer- Decreased CO2 Increased pH Right Shift - Answer- increased number of mature neutrophils Increased CO2 Decreased pH Increased 2,3 DPG