msn 611 exam 1 map Questions
with Answers
1. What cells released histamine? - --Mast cells
-ECL cells of the stomach
-1. Under what two circumstances may second-generation antihistamines
cause drowsiness? - -When combined with medications that cause CNS
depression or alcohol
-1. Drugs typically used to treat the symptoms of an allergic reaction or
allergic rhinitis? - --H1 Antihistamines
-1. Type of antihistamines used to inhibit the secretion of gastric acid in
patients with gastrointestinal disorders. - --H2 antihistamines
-1. Indication of some first-generation antihistamines - --To treat
extrapyramidal symptoms in those taking antipsychotic
-Motion sickness and nausea
-1. Second-generation antihistamines are preferred for treating which
patient category? - -children and geriatric
-1. Eosinophils, neutrophils, and T cells contain the type of histamine
receptors referred to as what? - --H4 receptors
-Inflammation and other allergic responses
-1. Compare and contrast first-generation antihistamines, second-generation
antihistamines - --First generation crosses BBB, second generation does not
-Equal efficiency in treating allergic response
-Second generation has less sedating, antimuscarinic, and anticholinergic
properties than first generation
-Second generation more commonly used for chronic allergic responses
-1. What is the advantage of second generation antihistamine? - --Less
sedating, anticholinergic, and antimuscarinic side effects
-1. Why 1st generation antihistamines are more sedating than 2nd
generation antihistamines? - -cross the BB
-1. What are 2nd generation antihistamines? - --Acrivastine
-Cetrizine
-Desloratidine
-Fexofenadine
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