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MSN 611 EXAM/99 QUESTIONS AND ANSWERS/A+ RATED
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MSN 611 EXAM/99 QUESTIONSAND ANSWERS/A+ RATED
Where are H4 receptors located? - -predominantly found on eosinophils,
neutrophils, and T cells.
-In the stomach, histamine is released by: - -enterochromaffin-like (ECL)
cells
-Toxic effect of first-generation antihistamines - -cardiac arrhythmias
-Anaphylaxis and Antihistamine - -Steroids may be added as adjunct
therapy
-Central nervous system side effect of antihistamines that elderly patients
should be aware of - -fatigue
-Indication of H2 antihistamines used - -used to inhibit the secretion of
gastric acid in patients with gastrointestinal (GI) disorders
-Which of the following is a second-generation antihistamine that cannot be
removed by hemodialysis? - -Cetirizine (Zyrtec)
-Initial selection of antimicrobial therapy is: - -Initial selection of
antimicrobial therapy is typically empiric, meaning before the causative
pathogen has been identified
-Food-drug or drug-drug interactions with antibacterial medications are
usually addressed by: - -This interaction is usually addressed by separating
the administration times or avoiding the combination
-Multiple drug combination treatment for tuberculosis - -It has decreased
risk of resistance
-Know about description of IFN-B - -FN-β products have antiviral properties
but are used for multiple sclerosis, not infections
-Side effect of first-generation antihistamines related to their anticholinergic
activity? - -dry mouth, dry eyes, urinary retention, constipation, and
cognitive disturbances. Anticholinergic side effects can be further
exacerbated by other anticholinergic medications, such as tricyclic
antidepressants (TCAs). Because monoamine oxidase inhibitors (MAOIs) can
also exacerbate anticholinergic side effects, first-generation antihistamines
, should not be used during treatment or within 2 weeks of MAOI
discontinuation
-How is enterobiasis diagnosed? - -Pinworm can be diagnosed by perianal
swab using adhesive tape that is examined microscopically for eggs
-Know tuberculosis treatment. - -Directly observed therapy (DOT) is a
strategy to ensure adherence to the drug regimen and is an especially
critical element to regimens with any frequency less than daily dosing.
Because these agents are highly susceptible to drug-drug interactions, any
exaggerated side effects or inadequate therapeutic responses when using
isoniazid and rifamin should be considered in light of potential drug
interactions with other medications the patient is taking concurrently.
-According to the universal prescribing alerts for aminoglycosides, extended
use increases risk for infection by which of the following pathogens? - -Can
cause C. difficile-associated diarrhea and pseudomembranous colitis with
extended use
-Systemic chemotherapy that is given prior to surgery or radiation serves to:
- -The use of systemic treatment to eliminate micrometastatic disease after
surgery or radiation is called adjuvant therapy. When it is administered, the
goal is to prevent recurrence of the cancer and improve survival. Systemic
therapy can also be given prior to surgery or radiation; in this case, it is
called neoadjuvant therapy. The purpose of neoadjuvant therapy is to reduce
the tumor burden and to increase the effectiveness of the local treatment.
-How is tumor lysis syndrome managed in leukemia patients? - -IV
hydration
-Acrolein is a toxic metabolite of cyclophosphamide and ifosfamide that can
cause: - -hemorrhagic cystitis
-Which category of antineoplastic drugs offers an alternative when
traditional treatments fail? - -Immunosupressant antineoplastic agents
-Topoisomerase inhibitors target enzymes that control changes in DNA - -
structure
-Which method is used to administer dactinomycin? - -only by the
intravenous route
-FDA-approved indication for methotrexate? - -Meningeal leukemia
Trophoblastic neoplasms
Breast cancer
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