NUR651 FINAL BRADLEY
UNIVERSITY QUESTIONS AND
ANSWERS 100% SOLVED EDITION
Which of the types of chemical bonding between drugs and their receptors is the least
common?✔✔ Covalent
Which type of drug classification is most important to the practitioner?✔✔ Therapeutic
Mechanism of Action✔✔ The manner in which molecular targets are affected by the drug
Adverse Drug Reaction (ADR) can lead the patient to✔✔ stop taking the drug
Half-life is defined as✔✔ The time required for the plasma concentration of a drug to be reduced
by 50 percent
When one drug is more efficacious than another, it has...✔✔ A greater ability to initiate a
response
What is bioavailability?✔✔ The fraction of unchanged drug that reaches the systemic circulation
following administration by any route
Absorption is defined as:✔✔ The transfer of a drug from its site of administration to the blood
How can Competitive antagonism be overcome?✔✔ by adding more agonist
How is children's dosing most often calculated?✔✔ MG/KG
A patient complains of pain from a migraine. How would the practitioner classify this type of
pain?✔✔ Central Neuropathic Pain
What stage of nociception is occurring when neurotransmitters in the dorsal horn directly or
indirectly depolarize the second-order neurons?✔✔ Trasmission
What are the four processes of Nociception✔✔ transduction, transmission, modulation, and
perception
A practitioner conducting a pain assessment asks the patient, "Is the pain consistent or
intermittent?" What character of pain is the practitioner assessing?✔✔ Temporal pattern
, What is the maximum dose of acetaminophen in 24 hours?✔✔ 4 grams
Etodolac is in the same drug class as ibuprofen. What is its mechanism of action?✔✔ It inhibits
the cyclooxygenase enzyme.
What kind of drug is Naloxone (Narcan)✔✔ opioid antagonist
Acetaminophen and alcohol have a complex relationship in the liver. Why? (3 reasons)✔✔ 1.
They are both metabolized by the same liver enzyme.
2. Alcohol inhibits the enzyme that metabolizes acetaminophen.
3. The enzyme that metabolizes acetaminophen is induced by alcohol.
What is a contraindication of ibuprofen?✔✔ Ulcers
An adverse effect of opiates in elders is...✔✔ Bone fractures
Aspirin is different from the other NSAIDs because...✔✔ It binds irreversibly to the COX
enzyme
One of the properties that insulins are differentiated by is...✔✔ Duration of action
Which form of insulin is the most bioavailable?✔✔ Humalog
What is the mechanism of action of sitagliptin (Januvia)?✔✔ Slows the inactivation of incretin
hormones by inhibiting dipeptidyl peptidase 4
How does canagliflozin (Invokana) control blood glucose levels?✔✔ By reducing glucose
reabsorption in the kidneys
What is the mechanism of action of Lantus?✔✔ Insulin precipitates into crystals and is slowly
absorbed over 24 hours
The most common complication of insulin therapy is...✔✔ Hypoglycemia
What is the mechanism of action of the sulfonylureas?✔✔ Increases insulin secretion
What drug is the first-line therapy for type 2 diabetes?✔✔ Metformin
What are the primary symptoms of ketoacidosis?✔✔ Excessive thirst and frequent urination
Type 2 diabetes is diagnosed when the A1C value is over:✔✔ 6.5%
UNIVERSITY QUESTIONS AND
ANSWERS 100% SOLVED EDITION
Which of the types of chemical bonding between drugs and their receptors is the least
common?✔✔ Covalent
Which type of drug classification is most important to the practitioner?✔✔ Therapeutic
Mechanism of Action✔✔ The manner in which molecular targets are affected by the drug
Adverse Drug Reaction (ADR) can lead the patient to✔✔ stop taking the drug
Half-life is defined as✔✔ The time required for the plasma concentration of a drug to be reduced
by 50 percent
When one drug is more efficacious than another, it has...✔✔ A greater ability to initiate a
response
What is bioavailability?✔✔ The fraction of unchanged drug that reaches the systemic circulation
following administration by any route
Absorption is defined as:✔✔ The transfer of a drug from its site of administration to the blood
How can Competitive antagonism be overcome?✔✔ by adding more agonist
How is children's dosing most often calculated?✔✔ MG/KG
A patient complains of pain from a migraine. How would the practitioner classify this type of
pain?✔✔ Central Neuropathic Pain
What stage of nociception is occurring when neurotransmitters in the dorsal horn directly or
indirectly depolarize the second-order neurons?✔✔ Trasmission
What are the four processes of Nociception✔✔ transduction, transmission, modulation, and
perception
A practitioner conducting a pain assessment asks the patient, "Is the pain consistent or
intermittent?" What character of pain is the practitioner assessing?✔✔ Temporal pattern
, What is the maximum dose of acetaminophen in 24 hours?✔✔ 4 grams
Etodolac is in the same drug class as ibuprofen. What is its mechanism of action?✔✔ It inhibits
the cyclooxygenase enzyme.
What kind of drug is Naloxone (Narcan)✔✔ opioid antagonist
Acetaminophen and alcohol have a complex relationship in the liver. Why? (3 reasons)✔✔ 1.
They are both metabolized by the same liver enzyme.
2. Alcohol inhibits the enzyme that metabolizes acetaminophen.
3. The enzyme that metabolizes acetaminophen is induced by alcohol.
What is a contraindication of ibuprofen?✔✔ Ulcers
An adverse effect of opiates in elders is...✔✔ Bone fractures
Aspirin is different from the other NSAIDs because...✔✔ It binds irreversibly to the COX
enzyme
One of the properties that insulins are differentiated by is...✔✔ Duration of action
Which form of insulin is the most bioavailable?✔✔ Humalog
What is the mechanism of action of sitagliptin (Januvia)?✔✔ Slows the inactivation of incretin
hormones by inhibiting dipeptidyl peptidase 4
How does canagliflozin (Invokana) control blood glucose levels?✔✔ By reducing glucose
reabsorption in the kidneys
What is the mechanism of action of Lantus?✔✔ Insulin precipitates into crystals and is slowly
absorbed over 24 hours
The most common complication of insulin therapy is...✔✔ Hypoglycemia
What is the mechanism of action of the sulfonylureas?✔✔ Increases insulin secretion
What drug is the first-line therapy for type 2 diabetes?✔✔ Metformin
What are the primary symptoms of ketoacidosis?✔✔ Excessive thirst and frequent urination
Type 2 diabetes is diagnosed when the A1C value is over:✔✔ 6.5%
