Summary
Summary NURS 350 PATHOPHYSIOLOGY : ALL DIAGRAMS [ ARIZONA COLLEGE OF NURSING]
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NURS 350 PATHOPHYSIOLOGY : ALL DIAGRAMS [ ARIZONA COLLEGE OF NURSING]
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PathophysiologyPrecipitating Factors:
exposure to radiation
Predisposing
ETIOLOGY: and certain chemicals
Factors:
Unknown having a sibling with
Age
leukemia
Gender
HTLV-1 virus
Race
genetic abnormalities
Family HIstory
Somatic mutations in chromosomal
the DNA translocations
Activate oncogene/
deactivate tumor-
supppresor gene
Malignant transformation
of lymphoid stem cells
s/sx:
Uncontrolled proliferation bone pain Treatment:
of lymphoblast in the bone joint pain Analgesic
marrow
Diagnostic Treatment:
Test: Lymphoblast replace the Remission
BM aspiration normal marrow elements Induction Therapy
BM biopsy Consolidation and
Maintenance
Therapy
BM Transplantation
CNS prophylaxis
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