NR 565 WEEK 4 MIDTERM EXAM LATEST 2023-2024 QUESTIONS WITH
CORRECT ANSWERS|AGRADE
1. A patient’s nutritional intake and laboratory results reflect
hypoalbuminemia. This is critical to prescribing because:
Distribution of drugs to target tissue may be affected.
2. Drugs that have a significant first-pass effect:
Are rapidly metabolized by the liver and may have little if any desired
action
3. The route of excretion of a volatile drug will likely
be the: Lungs
4. Medroxyprogesterone (Depo Provera) is prescribed intramuscularly
(IM) to create a storage reservoir
Increase the length of time a drug is available and active
5. The NP chooses to give cephalexin every 8 hours based on knowledge
of the drug’s: Biological half-life
6. Azithromycin dosing requires that the first day’s dosage be twice those of
the other 4 days of the prescription. This is considered a loading dose.
A loading dose:
Rapidly achieves drug levels in the therapeutic range
7. The point in time on the drug concentration curve that indicates the
first sign of a therapeutic effect is the:
Onset of action
8. Phenytoin requires that a trough level be drawn. Peak and trough
levels are done: To determine if a drug is in the therapeutic
range
9. A laboratory result indicates that the peak level for a drug is above the
minimum toxic concentration. This means that the:
Concentration will produce an adverse response
10. Drugs that are receptor agonists may demonstrate
what property? Desensitization or
downregulation with continuous use
11. Drugs that are receptor antagonists, such as beta blockers,
may cause: An exaggerated response if abruptly
,NR 565 WEEK 4 MIDTERM EXAM LATEST 2023-2024 QUESTIONS WITH
CORRECT ANSWERS|AGRADE
discontinued
12. Factors that affect gastric drug absorption
Begin distribution into the body immediately
14. When a medication is added to a regimen for a synergistic effect, the
combined effect of the drugs is:
Greater than the sum of the effects of each drug individually
15. Which of the following statements about bioavailability is true?
Bioavailability issues are especially important for drugs with narrow
therapeutic ranges or sustained-release mechanisms.
16. Which of the following statements about the major distribution barriers
(blood-brain or fetal- placental) is true?
The blood-brain barrier slows the entry of many drugs into and from
brain cells.
17. Drugs are metabolized mainly by the liver via phase I or phase II reactions.
The purpose of both of these types of reactions is to:
Change drug molecules to a form that an excretory organ can excrete
18. Once they have been metabolized by the liver, the
metabolites may be: More active than the parent
drug
Less active than the parent drug
Totally “deactivated” so they are excreted without any effect
19. All drugs continue to act in the body until they are changed or excreted.
The ability of the body to excrete drugs via the renal system would be
increased by:
Unbinding a nonvolatile drug from plasma proteins
20. Steady state is:
When the amount of drug in the body remains constant
21. Two different pain medications are given together for pain relief. The drug—
drug interaction Additive
22. Actions taken to reduce drug—drug interaction problems include all of
the following EXCEPT:
Prescribing a third drug to counteract the adverse reaction of the
combination
, NR 565 WEEK 4 MIDTERM EXAM LATEST 2023-2024 QUESTIONS WITH
CORRECT ANSWERS|AGRADE
23. Phase I oxidative-reductive processes of drug metabolism require
certain nutritional elements. Which of the following would
reduce or inhibit this process?
Neither Protein malnutrition OR Iron-deficiency anemia
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