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Reproductive System Pharmacology Course Notes - Easy Simple Concise Understood

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This concise class note provides students with easy simple and understood information about drugs acting on male and female reproductive systems, including: - gonadotropins (pituitary & non-pituitary) - sex hormonal drugs - drugs affecting uterus & cervix - drugs affecting sexual desire (aphrod...

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  • February 3, 2024
  • 36
  • 2023/2024
  • Class notes
  • Abubakr el-mahmoudy
  • All classes
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Drugs affecting the Reproductive System
Classification
Drugs acting on the reproductive system are classified acc. to
their nature of action into the following groups:

Gonadotropins

Sex hormones

Drugs affecting the uterus

Cervical dilators

Drugs affecting the sexual desire

, I- GONADOTROPINS
Members:
1- Pituitary gonadotropins:
FSH (Follicle Stimulating Hormone)

LH (Luteinizing Hormone)


2- Non-Pituitary gonadotropins:
PMS (Pregnant mare serum)

HCG (Human chorionic gonadotropin)

, PITUITARY GONADOTROPINS
Members:
FSH (Follicle Stimulating H.) & LH (Luteinizing H.)

Release control:
Under the effects of hypothalamic gonadotropin-RHs.
Follicle Stimulating hormone-releasing hormone (FSH-RH)
Luteinizing hormone-releasing hormone (LH-RH)

Actions:
- ↑ vascularity & thus activity of gonads,
leading to:

, PITUITARY GONADOTROPINS 2/3
FSH LH

Development of ovarian Maturation of ovarian
follicles ( ). follicles ( )
Spermatogenesis ( ). Ovulation ( )

Maintenance of CL &
synthesis and release of
progesterone ( )

Synthesis & release of Synthesis & release of
estradiol ( ). testosterone ( )

Puberty ( ). Puberty ( )

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