What is a bound hormone? Correct Ans - Transported through
protein carriers
Why do free hormones need to be free? Correct Ans - To send the
message to the target tissue
What is the hypothalamus-pituitary-hormone axis? Correct Ans -
Primary: at site of gland, Secondary: Pituitary gland, Tertiary:
Hypothalamus
What is the composition of the pituitary gland? Correct Ans -
Comprised of hypothalamus's, anterior pituitary gland, and posterior
pituitary gland
What is the role of the hypothalamus? Correct Ans - Regulates the
synthesis and secretion of pituitary gland hormones
What are the hormones secreted by the anterior pituitary gland?
Correct Ans - Growth Hormone, Thyroid Stimulating hormone,
Adrenocortical hormone, follicle stimulating hormone, luteinizing
hormone, prolactin, Melanocyte-stimulating hormone
What are the hormones secreted by the posterior pituitary gland?
Correct Ans - ADH, Oxytocin
What is ADH? Correct Ans - Antidiuretic hormone
What is the function of ADH? Correct Ans - Anti-urine products
Why is ADH essential? Correct Ans - To maintain body's fluid
balance
What is Diabetes insipidus? Correct Ans - Excess water loss due to
decreased ADH secretion/renal response to ADH
What are the clinical manifestations of Diabetes insipidus? Correct Ans
- Extreme thirst, polyuria, dehydration, bed wetting, hypernatremia
, What are the causes of Neurogenic (central) Diabetes insipidus?
Correct Ans - Head injury, brain surgery, gestational
What are the causes of Nephrogenic Diabetes insipidus? Correct Ans -
Congenital, pyelonephritis, lithium toxicity, electrolyte disorders
What is Syndrome of Inappropriate Antidiuretic Hormone (SIADH)?
Correct Ans - Too much ADH, too much water retention
What are the clinical manifestations of Syndrome of Inappropriate
Antidiuretic Hormone (SIADH)? Correct Ans - Water intoxication,
diluted blood, decreased urine output
What are the causes of Syndrome of Inappropriate Antidiuretic Hormone
(SIADH)? Correct Ans - Surgery/trauma relating to ADH,
pain/stress, temp changes, HIV, conditions that affect CNS
What is Gigantism? Correct Ans - Excess of GH before puberty and
before fusion of long bones
What are the clinical manifestations of Gigantism? Correct Ans -
Increased height
What is Acromegaly? Correct Ans - GH excess after puberty/fusion
of long bones
What are the clinical manifestations of Acromegaly? Correct Ans -
No increase in height, soft tissues continue to grow, bones in
hands/feet/face continue to grow along with muscles
What are the causes of decreased secretion of growth hormone in adults?
Correct Ans - Preexisting from childhood, pituitary tumor, treatment of
pituitary gland
What are the clinical manifestations of decreased secretion of growth
hormone in adults? Correct Ans - Decrease in lean body mass,
increase in fat mass, hyperlipidemia, reduced exercise capability
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