OCN EXAM (2024) Q & A
" B Symptoms": Associated w lymphoma diagnoses Answer- Fever Night-sweats
Weight loss
Prurirtus
Carry a poorer prognosis
Tyrosine Kinase Inhibitors Answer- antineoplastic agents- interfere w cell communication and growth by inhibiting the tyrosine kinase enzyme-
ex: Sunitinib ( used in gastric stroma tumors & renal cell ca)
Common CA w/ Brain metastases Answer- Melanoma
Breast Lung
Renal
Colon
Neoplastic Cardiac Tamponade Answer- Fluid collection around the heart- most common in breast ca, leukemia, and lymphoma
ONC EMERGENCY
Neoplastic Cardiac tamponade s/s Answer- Tachycardia
Decreased SBP
Increased CVP
Vasoconstriction
Pulsus paradoxus
JVD
Beck's triad for cardiac tamponade. Answer- (1) HYPOTENSION
(2) MUFFLED or DISTANT HEART SOUNDS
(3) JUGULAR VENOUS DISTENSION (JVD) w/ Increased CVP
Tx: PERICARDIOCENTESIS
TX of choice in bladder CA that has invaded surrounding muscle Answer- Radical Cystectomy
renal cell carcinoma s/s Answer- HTN Cushings
Non-metastatic Hepatopathy
Hypercalcemia
Erythrocytosis
Pyrexia
Galactorrhea
Gynecomastia
Serum glucose abnormalities
Plummer-Vinson syndrome Answer- (ass. with gastric CA)
weakness and difficulty swallowing d/t small growths of tissue in esophagus
Renal Cell Metastases sites Answer- Bone
Soft tissue
Liver
Lung
Most commonly diagnosed CA in US Answer- Prostate CA
(increased prevalence in AA men)
radical prostatectomy Answer- Not indicated in advanced disease
Advanced prostate cancer treatment Answer- Chemotherapy, Clinical trials, external
beam radiation, hormonal therapy
Stage T2 - Prostate Cancer Answer- clinically palpable tumor confined to prostate
Cabazitaxel (Jevtana) Answer- Indicated in hormone refectory metastatic prostate ca
Leuprolide acetate (Lupron) Answer- Gonadotropin relating hormone
used in palliative tx of advanced prostate ca
Cryptochidism Answer- undescended testes; the condition in which the testes do not
descend to the scrotum as they should during prenatal development
x5 increase for testicular ca
s/s of testicular cancer Answer- scrotal "fullness or heaviness," may NOT experience pain, dull ache in lower abdomen, groin, or back, lump in testicle, gynocomastia
tumor lysis syndrome Answer- Increased risk in hematological CA w/ Increased LDH
& increased tumor burden
It is characterized by hyperphosphatemia, hypocalcemia, hyperkalemia (EKG changes), and hyperuricemia.
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