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Karch Focus on Nursing Pharmacology Chapter 1 Questions and Correct Answers.
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Karch Focus on Nursing PharmacologyChapter 1 Questions and Correct
Answers
Adverse Effects - correct answers:drugs effects that are not to the desired therapeutic affects; may be
unpleasant or even dangerous
Brand Name - correct answers:name given to a drug the pharmaceutical company that developed it; also
called a trade name
Chemical Name - correct answers:name that reflects the chemical structure of a drug
Drugs - correct answers:chemicals that are introduced into the body to bring about some sort of change
FDA - correct answers:federal agency responsible for the regulation and enforcement of drug evaluation
and distribution policies
Generic Drugs - correct answers:drugs sold by their chemical name, not brand or trade name products
Generic Name - correct answers:the original designation that a drug is given when the drug company
that develops it applies for the approval process
Genetic Engineering - correct answers:process of altering DNA, usually of bacteria, to produce a chemical
to be used as a drug
Orphan Drugs - correct answers:drugs that have been discovered but would not be profitable for a drug
company to develop; usually drugs that would treat only a small number of people; these orphans can
be adopted by drug companies to be developed
Over the Counter OTC - correct answers:available without a prescription for self treatment of a variety of
complaints, deemed to be safe if used as directed
, Pharmacology - correct answers:the study of the biological effects of chemicals
Pharmacotherapeutics - correct answers:clinical pharmacology-the branch of pharmacology that deals
with drugs; chemicals that care used in medicine for the treatment, prevention and diagnosis of disease
in humans
Steps involved in developing/approving new drug in the U.S - correct answers:*preclinical
*Phase I, II and III studies
*Once finish phase III evaluated by FDA
*Approved drug given brand name
*Phase IV continual evaluation
PreClinical Trials - correct answers:Chemicals tested on lab animals
Phase One Study - correct answers:Chemicals tested human volunteers for several months
Dropped If: too toxic, unacceptable adverse reactions, lack therapeutic effect in humans
Phase Two Study - correct answers:Drug tried on informed pt's
Dropped if: less effective than anticipated, too toxic, low benefit-to-risk ratio
Phase Three Study - correct answers:drug used in vast clinical market for those who have the disesase
Dropped if: unacceptable adverse effects/unforeseen reactions
Phase Four Study - correct answers:continual evaluation of a drug after it has been released for
marketing
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