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Contemporary Clinical Immunology and Serology by Rittenhouse Olson
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,Chapter 1 Introduction to ImmunologyMultiple-Choice Questions
1.
Which quadrant in the figure contains the smaller cell(s) with more granularity?
a. A
b. B
c. C
d. D
2. CD11c+ cells are
a. macrophage
b. B cells
c. T cells
d. dendritic cells
3. Apoptosis, also known as programmed cell death occurs when
a. the cell receives certain signals and then sends perforins to kill neighboring cells
b. the cell receives certain signals and digests its own DNA
c. the cell receives certain signals and digests its own membrane
d. none of the above
4. CD 56+, CD 16+, and CD3- are markers used to characterize–
a. a macrophage
b. an NK cell
C a dendritic cell
c. an eosinophil
5. An antigen-specific cell is a
a. neutrophil
b. T or B lymphocyte
c. macrophage
d. NK cell
6. A phagocytic cell is a(n)
a. platelet
b. T or B lymphocyte
c. macrophage
d. NK cell
©2013 by Pearson Education, Inc.
Rittenhouse-Olson/De Nardin, Contemporary Clinical Laboratory Immunology and Serology
,7. When treated with IL-2, this cell becomes an LAK cell.
a. neutrophil
b. T or B lymphocyte
c. macrophage
d. NK cell
8. The first cell at the site of an infection is a(n)
a. neutrophil
b. T or B lymphocyte
c. macrophage
d. NK cell
9. The cell of the following cell types that is called a Kupfer cell when in the liver is
a. neutrophil
b. T or B lymphocyte
c. macrophage
d. NK cell
10. A pattern recognition receptor is(are)
a. defensins and cathelicidins
b. unmethylated DNA, ss RNA
c. SALT
d. toll-like receptor
11. An acute phase reactant involved in cardiac risk measurements is(are)
a. defensins and cathelicidins
b. unmethylated DNA, ss RNA
c. SALT
d. C-reactive protein
12. Antimicrobial peptides is(are)
a. defensins and cathelicidins
b. unmethylated DNA, ss RNA
c. SALT
d. C-reactive protein
13. A pathogen associated molecular pattern is(are)
a. defensins and cathelicidins
b. Unmethylated DNA, ss RNA
c. SALT
d. C-reactive protein
14. A secondary lymphoid organ is(are)
a. defensins and cathelicidins
b. unmethylated DNA, ss RNA
c. SALT
d. C-reactive protein
©2013 by Pearson Education, Inc.
Rittenhouse-Olson/De Nardin, Contemporary Clinical Laboratory Immunology and Serology
, 15. The innate immune system uses
a. PRR to recognize PAMP
b. PAMP to recognize PRR
c. PAMP to recognize surface mannose
d. surface mannose to recognize lectins on the bacteria
16. CD19, 20, 21 are on these cells
a. macrophage
b. B cells
c. T cells
d. dendritic cells
17. Which of the following is involved in a humoral immune response?
a. neutrophil
b. B lymphocyte
c. macrophage
d. NK cell
e. T cells
18. Which of the following has a polymorphic nucleus
a. neutrophil
b. B lymphocyte
c. macrophage
d. NK cell
e. T cells
19. Which of the following cells kills tumor cells and virally infected cells, not antigen specific, uses
perforins
a. neutrophil
b. B lymphocyte
c. macrophage
d. NK cell
20. The phagocytic cell that does not arrive first at the site of a chronic infection is the
a. neutrophil
b. B lymphocyte
c. macrophage
d. NK cell
e. T cell
21. The cell of the following cells that has a specific regulatory subset is a
a. neutrophil
b. B lymphocyte
c. macrophage
d. T cell
22. Each of the 12 types of these binds a different PAMP.
a. TLR
b. bacterial flagellin
c. tonsil
d. C-reactive protein
©2013 by Pearson Education, Inc.
Rittenhouse-Olson/De Nardin, Contemporary Clinical Laboratory Immunology and Serology
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