BMTCN Miscellaneous Questions and answers

A. L. is receiving an autologous transplant. During the stem cell infusion, A. L begins to feel chest tightness, flushing and is hypertensive. A.L. is most likely experiencing what type of reaction? a. Acute hemolytic reaction b. Urticarial reaction c. Dimethyl sulfoxide toxicity d. Anaphylactic reaction - ANSWER-c. Dimethyl sulfoxide toxicity 2.Which of the following is an immunologic complication of cellular therapy? a. Circulatory overload b. Anaphylactic reaction c. Dimethyl sulfoxide toxicity d. Septic infusion reactions - ANSWER-b. Anaphylactic reaction Which of the following is NOT an immunologic complication of cellular therapy? a. GVHD b. Anaphylactic Reaction c. Transfusion-Related Acute Lung Injury d. Circulatory Overload - ANSWER-d. Circulatory Overload What is the most common adverse effect for non-cryopreserved cellular therapy products? a. Acute hemolytic reaction b. Anaphylactic reaction c. Dimethyl sulfoxide toxicity d. Febrile nonhemolytic reactions - ANSWER-a. Acute hemolytic reaction Within how many days prior to donor stem cell mobilization, collection, or initiation of recipient's preparative regimen must a pregnancy test for childbearing female be performed? - ANSWER-7 days Name 2 regulatory bodies that publish requirements for donor evaluation? - ANSWER-FACT, F