PC707 Black Box Warnings & Contraindications Exam Questions and Answers 100% Pass

PC707 Black Box Warnings & Contraindications Exam Cox 2 Inhibitors (Celecoxib - Celebrex) - Answer ️️ -Increased risk for cardiovascular events. (Treats arthritis) Phenytoin (Dilantin) - Answer ️️ -Cardiac event if rapid IV administration. In Pregnancy: Neural tube defects in 1st trimester SSRIs (Citalopram/celexa, Escitalopram/Lexapro, fluoxetine/prozac, paroxetine/paxil, vilazodone/viibryd) - Answer ️️ -Suicidal ideation In pregnancy: May increase risk of neurobehavioral disruptions Paxil: increase in congenital cardiac malformations in 1st trimester, pulmonary HTN in 3rd trimester, prematurity and low birth weight Fluroquinolones (Levaquin/Cipro) - Answer ️️ -tendon rupture Phenothiazine (Histamine Agonist) Promethazine (neuroleptic - trade name Phenergan) - Answer ️️ -QT prolongation and respiratory distress in children under 2 Metoclopramide/Reglan - Answer ️️ -Tardive dyskinesia LABA (Long Acting Beta Agonist) (Advair, Symbicort) - Answer ️️ -death in asthma pts if used as emergency/rescue inhaler. Must use albuterol. Lamotrigine (Lamictal) (to treat epilepsy and bipolar disorder) - Answer ️️ -Stevens Johnson Syndrome Breastfeeding: associated with numerous adverse effects, used only if no alternative Metformin - Answer ️️ -Lactic Acidosis - rare but 50% fatal Ultram (Tramadol) (Analgesic opioid) - Answer ️️ -Seizure Risk. Do not prescribe with hx of head trauma or current alcohol use. Singulair - Answer ️️ -Aggression, dreams and suicidal thoughts Opioids & Benzos - Answer ️️ -Respiratory failure if given together Carbemazepine (Tegretol) - (for epilepsy and neuropathic pain) - Answer ️️ -Stevens Johnson Syndrome, also drug drug interactions with contraceptives. Nitrofurantoin (Macrobid) - Answer ️️ -Not BBW but Adv. Eff: Pulmonary Toxicity