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NR 565 Advanced Pharmacology Midterm Exam 2025- Chamberlain Actual Questions with 100% Correct Answers | Updated 2025 / 2026 & Verified $13.99
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NR 565 Advanced Pharmacology Midterm Exam 2025- Chamberlain Actual Questions with 100% Correct Answers | Updated 2025 / 2026 & Verified

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1. During what trimester is a pregnant woman most at risk for adverse drug reactions with potential long term consequences? ANS 1st trimester (fetus most at risk d/t rapid growth) 2. What is BEERS criteria? ANS Recommendations of medications inappropriate for elderly (65 and older), prescriber u...

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  • March 4, 2024
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NR 565 - ADVANCED PHARMACOLOGY
MIDTERM - CHAMBERLAIN
1.During what trimester is a pregnant woman most at risk for adverse drug

reactions with potential long term consequences?

ANS 1st trimester (fetus most at risk d/t rapid growth)

2.What is BEERS criteria?

ANS Recommendations of medications inappropriate for elderly (65

and older), prescriber ultimately decides

3.What is the CYP450 (cytochrome P450)

ANS liver enzyme system where medica- tions are metabolized, can

either be inducers or inhibitors and create drug-drug interactions

4.CYP450 inducers

ANS Speed up metabolism of drugs (drug is cleared faster), drug has

lesser effect (decrease blood levels of drug), elevate CYP450 enzymes

5.CYP450 inducers pneumonic

ANS "Bullshit Crap GPS INDUCES rage"

6.CYP450 inducer drug names

ANS Barbituates, St John wort, Carbamazepine, ri- fampin, alcohol,



,phenytoin, griseofulvin, phenobarbital, sulfonylureas

7.CYP450 inhibitors

ANS inhibit metabolism, increase blood levels of medications

8.CYP450 pneumonic

ANS "VISA credit card debt INHIBITS spending on designers like CK to

look GQ"

9.CYP450 inhibitors drug names

ANS Valproate, isoniazid, sulfonamides, amio- darone,

chloramphenicol, ketoconazole, grapefruit juice, quinidine

10.Physiological changes during pregnancy that impact

pharmacodynamics and pharmacokinetic properties of drugs?

ANS increase glomerular filtration rate leads to increase durg excretion

increase hepatic metabolism

decrease tone and motility of

bowel increase drug absorption

11.Examples of medications that can be teratogenic

ANS Antiepileptic drugs, an- timicrobials such as tetracyclines and

fluoroquinolones, vitamin A in large doses, some anticoagulants, and

hormonal medications such as diethylstilbestrol (DES).


,12.How is absorption of intramuscular medications different in neonates?

ANS -

slow and erratic due to low blood flow in muscles first few days of life

13.Why is absorption of medication in the stomach increased in infancy?

ANS de- layed gastric emptying

14.Some medications that should be avoided in the pediatric patient?

ANS glu- cocorticoids, discoloration of developing teeth with

tetracyclines, and kernicterus with sulfonamides, levofloxacin

(antibiotics)

aspirin (Severe intoxication from acute overdose)

15.what should be included in medication administration patient education?



ANS dosage size and timing

route and technique of

administration duration of

treatment






, drug storage

nature and time course of desired

responses nature and time course of

adverse responses finish taking

antibiotic

16.What are some things that put the elderly patient at higher risk for

adverse drug reactions?

ANS reduced renal function

polypharmacy (the use of five or more medications

daily) greater severity of illness

presence of comorbidities

use of drugs that have a low therapeutic index (e.g., digoxin)

increased individual variation secondary to altered

pharmacokinetics inadequate supervision of long-term

therapy

poor patient adherence

17.How can healthcare providers decrease likelihood of an elderly patient

experiencing an adverse drug reaction?

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