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Test bank for Huether & McCance: Understanding Pathophysiology, 6th Edition A+
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Test Bank Understanding Pathophysiology 6th EditionChapter 01: Cellular Biology
Huether & McCance: Understanding Pathophysiology, 6th Edition A+
MULTIPLE CHOICES
1. A student is observing a cell under the microscope. It is observed to have supercoiled DNA
with histones. Which of the following would also be observed by the student?
a. A single circular chromosome
b. A nucleus
c. Free-floating nuclear material
d. No organelles
ANS: B
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within its
nucleus; thus, the nucleus should be observed. A single circular chromosome called a
prokaryote contains free-floating nuclear material but has no organelles.
REF: p. 2
2. A nurse is instructing the staff about cellular functions. Which cellular function is the nurse
describing when an isolated cell absorbs oxygen and uses it to transform nutrients to energy?
a. Metabolic absorption
b. Communication
c. Secretion
d. Respiration
ANS: D
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, Test Bank Understanding Pathophysiology 6th Edition
The cell’s ability to absorb oxygen is referred to as respiration while its communication ability
involves maintenance of a steady dynamic state, metabolic absorption provides nutrition, and
secretion allows for the synthesizing of new substances.
REF: p. 2
3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would most of
the genetic information be contained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm
ANS: C
The region of the cell that contains genetic material, including a large amount of ribonucleic
acid, most of the DNA, and DNA-binding proteins, is the nucleolus, which is located within
the cell’s nucleus. Mitochondria is associated with cellular respiration, while ribosomes are
involved with protein manufacturing. Cytoplasm is a fluid filling that is a component of the
cell.
REF: p. 2
4. Which of the following can remove proteins attached to the cell’s bilayer by dissolving the
layer itself?
a. Peripheral membrane proteins
b. Integral membrane proteins
c. Glycoproteins
d. Cell adhesion molecules
ANS: B
Proteins directly attached to the membrane bilayer can be removed by the action of integral
membrane proteins that dissolve the bilayer. Peripheral membrane proteins reside at the
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, Test Bank Understanding Pathophysiology 6th Edition
surface while cell adhesion molecules are on the outside of the membrane. Glycoprotein
marks cells and does not float.
REF: p. 7
5. Which of the following can bind to plasma membrane receptors?
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, Test Bank Understanding Pathophysiology 6th Edition
a. Oxygen
b. Ribosomes
c. Amphipathic lipids
d. Ligands
ANS: D
Ligands are the only specific molecules that can bind with receptors on the cell membrane.
REF: p. 9
1. A nurse is reviewing a report from a patient with metastatic cancer. What alteration in the extracellular matrix would
support the migration of metastatic cancer?
a. Decreased fibronectin
b. Increased collagen
c. Decreased elastin
d. Increased glycoproteins
ANS: A
Only a reduced amount of fibronectin is found in some types of cancerous cells, allowing them to travel or
metastasize.
REF: p. 10
2. Which form of cell communication is used to relate to other cells in direct physical contact? a. Cell junction
b. Gap junction
c. Desmosome
d. Tight junction
ANS: A
Cell junctions hold cells together and permit molecules to pass from cell to cell. Gap junctions allow for cellular
communication between cells. Neither desmosomes nor tight junctions are associated with cellular communication.
REF: p. 11
3. Pancreatic beta cells secrete insulin, which inhibits secretion of glucagon from neighboring alpha cells. This action is
an example of which of the following signaling types?
a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
Test Bank Page 4
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