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TEST BANK FOR UNDERSTANDING PATHOPHYSIOLOGY 1ST CANADIAN EDITION EL-HUSSEIN
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Test Bank for Huether and McCance's Understanding Pathophysiology, Canadian Edition, 2nd Edition by Kelly Power-Kean, Chapter 1 - 42
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TEST BANK FORUNDERSTANDING
PATHOPHYSIOLOGY 1ST
CANADIAN EDITION EL-
HUSSEIN
Test Bank for Understanding Pathophysiology, 1st Canadian Edition,
Mohamed El- Hussein, Kelly Power-Kean, Stephanie Zettel, Sue Huether,
Kathryn McCance, ISBN:9781771721189, ISBN: 9781771721172
Table of Contents
PART ONE: BASIC CONCEPTS OF PATHOPHYSIOLOGY
Unit 1: The Cell
• Cellular Biology
• Genes and Genetic Diseases
• Epigenetics and Disease
• Altered Cellular and Tissue Biology
• Fluids and Electrolytes, Acids and Bases
Unit 2: Mechanisms of Self-Defense
• Innate Immunity: Inflammation and Wound Healing
• Adaptive Immunity
• Infection and Defects in Mechanisms of Defense
• Stress and Disease
Unit 3: Cellular Proliferation: Cancer
• Biology of Cancer
• Cancer Epidemiology
• Cancer in Children and Adolescents
PART TWO: BODY SYSTEMS AND DISEASES
Unit 4: The Neurologic System
• Structure and Function of the Neurologic System
• Pain, Temperature, Sleep, and Sensory Function
, • Alterations in Cognitive Systems, Cerebral Hemodynamics and Motor Function
• Disorders of the Central and Peripheral Nervous Systems and Neuromuscular Junction
• Alterations of Neurologic Function in Children
Unit 5: The Endocrine System
• Mechanisms of Hormonal Regulation
• Alterations of Hormonal Regulation
Unit 6: The Hematologic System
• Structure and Function of the Hematologic System
• Alterations in Hematologic Function
• Alterations of Hematologic Function in Children
Unit 7: The Cardiovascular and Lymphatic Systems
• Structure and Function of the Cardiovascular and Lymphatic Systems
• Alterations of Cardiovascular Function
• Alterations of Cardiovascular Function in Children
Unit 8: The Pulmonary System
• Structure and Function of the Pulmonary System
• Alterations of Pulmonary Function
• Alterations of Pulmonary Function in Children
Unit 9: The Renal and Urologic Systems
• Structure and Function of the Renal and Urologic Systems
• Alterations of Renal and Urinary Tract Function
• Alterations of Renal and Urinary Tract Function in Children
Unit 10: The Reproductive Systems
• Structure and Function of the Reproductive Systems
• Alterations of the womanReproductive System
• Alterations of the Male Reproductive System
Unit 11: The Digestive System
• Structure and Function of the Digestive System
• Alterations of Digestive Function
• Alterations in Digestive Function in Children
Unit 12: The Musculoskeletal and Integumentary Systems
• Structure and Function of the Musculoskeletal System
• Alterations of Musculoskeletal Function
• Alterations of Musculoskeletal Function in Children
• Structure, Function, and Disorders of the Integument
• Alterations of the Integument in Children
Chapter 01: Cellular Biology
,MULTIPLE
CHOICE
• A student is observing a cell under the microscope. It is observed to have
supercoiled DNAwith histones. Which of the following would also be observed by
the student?
• A single circular chromosome
• A nucleus
• Free-floating nuclear material
• No organelles
ANS: B
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA
within its nucleus; thus, the nucleus should be observed. A single circular
chromosome called a prokaryote contains free-floating nuclear material but has no
organelles.
REF: p. 2
• A nurse is instructing the staff about cellular functions. Which cellular function is
the nurse describing when an isolated cell absorbs oxygen and uses it to transform
nutrients to energy?
• Metabolic absorption
• Communication
• Secretion
• Respiration
ANS: D
The cell’s ability to absorb oxygen is referred to as respiration while its communication
ability
involves maintenance of a steady dynamic state, metabolic absorption provides
nutrition, andsecretion allows for the synthesizing of new substances.
REF: p. 2
• A eukaryotic cell is undergoing DNA replication. In which region of the cell would
most ofthe genetic information be contained?
• Mitochondria
• Ribosome
• Nucleolus
• Nucleus Cytoplasm
ANS: C
The region of the cell that contains genetic material, including a large amount of
ribonucleicacid, most of the DNA, and DNA-binding proteins, is the nucleolus,
which is located within the cell’s nucleus. Mitochondria is associated with cellular
, respiration, while ribosomes are involved with protein manufacturing. Cytoplasm is
a fluid filling that is a component of the cell.
REF: p. 2
• Which of the following can remove proteins attached to the cell’s bilayer by
dissolving the layer itself?
• Peripheral membrane proteins
• Integral membrane proteins
• Glycoproteins
• Cell adhesion molecules
ANS: B
Proteins directly attached to the membrane bilayer can be removed by the action of
integralmembrane proteins that dissolve the bilayer. Peripheral membrane proteins
reside at the surface while cell adhesion molecules are on the outside of the
membrane. Glycoprotein marks cells and does not float.
REF: p. 7
• Which of the following can bind to plasma membrane receptors?
• Oxygen
• Ribosomes
• Amphipathic lipids
• Ligands
ANS: D
Ligands are the only specific molecules that can bind with receptors on the cell
membrane.
REF: p. 9
•
• A nurse is reviewing a report from a client with metastatic cancer. What
alternation in theextracellular matrix would suN
ppoR
rt thIe dG
iagnBo.
siC
s ofM
metastatic
cancer?
• Decreased fibronectin
• Increased collagen
• Decreased elastin
• Increased glycoproteins
ANS: A
Only a reduced amount of fibronectin is found in some types of cancerous cells,
allowingthem to travel or metastasize.
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