APHON Principles of Chemo and Biotherapy, Top
Questions and answers, 100% Accurate. Verified.
1). Biotherapy
Ans: Targeted anticancer agents also known as biological response modifiers (BRM)
2). Tyrosine kinase inhibitors (tkis) are what class
Ans: Biotherapy
3). Monoclonal antibodies (moabs) are what class
Ans: Biotherapy
4). Define pharmacokinetics
Ans: Study of drug absorption, metabolism, and excretion
5). Define pharmacodynamics
Ans: The concentration of the drug in the body and how it produces a response
6). Define adjuvant chemotherapy
Ans: The use of chemo after another type of therapy, such as surgery, to treat residual
disease or undetectable metastasis.
7). Define neoadjuvant chemotherapy
Ans: When chemo is used preoperatively to decrease tumor burden in order to make it
easier to remove the tumor surgically.
PaperStoc.com Page 1 of 7
, 8). Define sanctuary sites
Ans: Sites within the body where tumor cells sequester and are not easily reached by
chemo such as the CNS
9). What normal cells are most often effected by chemotherapy
Ans: Hematopoietic, mucosal (mouth & GI), hair follicles
10). Why use chemotherapy
Ans: To prevent cancer cells from dividing, metastasizing, and ultimately causing the
death of the patient
11). Cure
Ans: To permanently eradicate the cancer
12). Control
Ans: To extend the length & QOL when cure is not feasible or realistic
13). Palliation
Ans: Minimize pain and suffering during end of life
14). Resting phase of cell cycle
Ans: Gap 0 - cells not dividing
15). Postmitotic phase
Ans: Gap 1 - enzymes needed for DNA synthesis are produced, protein and RNA
synthesis takes place (18 Hours)
16). Synthesis (s) phase
Ans: Cellular DNA duplicated (20 hours)
17). Premitotic phase
PaperStoc.com Page 2 of 7
Questions and answers, 100% Accurate. Verified.
1). Biotherapy
Ans: Targeted anticancer agents also known as biological response modifiers (BRM)
2). Tyrosine kinase inhibitors (tkis) are what class
Ans: Biotherapy
3). Monoclonal antibodies (moabs) are what class
Ans: Biotherapy
4). Define pharmacokinetics
Ans: Study of drug absorption, metabolism, and excretion
5). Define pharmacodynamics
Ans: The concentration of the drug in the body and how it produces a response
6). Define adjuvant chemotherapy
Ans: The use of chemo after another type of therapy, such as surgery, to treat residual
disease or undetectable metastasis.
7). Define neoadjuvant chemotherapy
Ans: When chemo is used preoperatively to decrease tumor burden in order to make it
easier to remove the tumor surgically.
PaperStoc.com Page 1 of 7
, 8). Define sanctuary sites
Ans: Sites within the body where tumor cells sequester and are not easily reached by
chemo such as the CNS
9). What normal cells are most often effected by chemotherapy
Ans: Hematopoietic, mucosal (mouth & GI), hair follicles
10). Why use chemotherapy
Ans: To prevent cancer cells from dividing, metastasizing, and ultimately causing the
death of the patient
11). Cure
Ans: To permanently eradicate the cancer
12). Control
Ans: To extend the length & QOL when cure is not feasible or realistic
13). Palliation
Ans: Minimize pain and suffering during end of life
14). Resting phase of cell cycle
Ans: Gap 0 - cells not dividing
15). Postmitotic phase
Ans: Gap 1 - enzymes needed for DNA synthesis are produced, protein and RNA
synthesis takes place (18 Hours)
16). Synthesis (s) phase
Ans: Cellular DNA duplicated (20 hours)
17). Premitotic phase
PaperStoc.com Page 2 of 7
