100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Introduction to enzymes lecture note $12.49   Add to cart

Exam (elaborations)

Introduction to enzymes lecture note

1 review
 7 views  0 purchase
  • Course
  • Biochem
  • Institution
  • Biochem

Introduction to enzymes lecture note

Preview 3 out of 20  pages

  • April 3, 2024
  • 20
  • 2023/2024
  • Exam (elaborations)
  • Questions & answers
  • Biochem
  • Biochem

1  review

review-writer-avatar

By: Fordenken • 3 months ago

avatar-seller
QUALITYGRADES
Lecture 22- Enzymes of Diagnostic Importance




Lecture 22- Enzymes
of Diagnostic
Importance






, Lecture 22- Enzymes of Diagnostic Importance

What marker enzymes of diagnostics do we look for in the liver? What are

the names?: 1. Aspartate transaminase (AST)


1. Alanine transaminase (ALT)


2. Where are the liver enzymes localized, and describe their activity.:

Localization: ALT located in cytosol of hepatocytes exclusively; AST present in

cytosol and mitochondria of hepatocytes. It also expresses in muscle cells

(skeletal/cardiac muscles).

Activity: The activity of ALT in hepatocytes is very high when compared to AST 3.

What is the diagnostic importance of liver enzymes?: When liver cells are

damaged due to infections, inflammation etc (hepatitis, liver cirrhosis) abnormal

amounts of these 2 enzymes are released in the bloodstream. The levels of ALT

and AST serve as important markers of impaired liver function and play an

important role in assessing and monitoring the degree of hepatocyte damage in

the liver.






, Lecture 22- Enzymes of Diagnostic Importance
.
4. What is ALP? What are they important in? Where are they localized?

Where can they be present in high concentrations in?: Alkanline phosphatase

(ALP): is a group of enzymes that dephosphorylates proteins, nucleic acids and

alkaloids at a higher pH.

5. ALP as a SIGNIFICANT marker of what specific condition? Describe this

condition and its symptoms.: Cholestasis

6. In order to use enzyme markers for a clinical diagnosis, what must a

physician check for?Clinical Diagnosis of a Disease using Enzyme Markers:

1)

Presence/absence of marker enzymes in plasma/serum


2) Change in enzyme conc.: Plasma/serum/ cellular concentration (see if there

is a drastic change)

3) Change in enzyme localization-mitochondrial enzymes when mito is

damaged will be released into the blood 4) Pattern of enzyme clearance

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller QUALITYGRADES. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $12.49. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

79373 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$12.49
  • (1)
  Add to cart