CBC - Complete Blood Count exam with complete solutions

CBC - Complete Blood Count exam with complete solutions Components of a CBC - Correct Answer White blood cell count and differential Red blood cell count Red blood cell indices Mean corpuscular volume (MCV) Mean corpuscular hemoglobin (MCH) Mean corpuscular hemoglobin concentration (MCHC) Red cell distribution width (RDW) Hematocrit (Hct) Hemoglobin (Hgb) Peripheral smear Platelet count CBC Indications - Correct Answer CBC can help: Make a diagnosis Narrow the differential diagnoses Guide further diagnostic testing Complaints supporting CBC - Correct Answer Fever Fatigue Dyspnea Bleeding Bruising Petechiae Heme positive stools Weight loss, unexplained Lymphadenopathy Dizziness (not vertigo) Palpitations Angina Jaundice Abdominal pain And the list continues... Development of Blood Cells (Orignates from, differentiates to what? - Correct Answer Hemocytoblast - Common myeloid progenitor and common lymphoid progenitor Common myeloid progenitor differentates into Megakaryocytes(make thrombocytes), erythrocysts, mast cells, and myeloblast. Myelobase differents into 4/5 of the WBC -- Neutrophil, Basophil, Eosinphil, and Monocyte(makes Macrophages) Common lymphoid progenitor differentates into large granular lymphocytes(natural killer cells) and small lymphocytes which differentiate into T lymphocytes and B lymophocytes(which produces plasma cells which produces antibodies) What do White Blood Cells (WBCs) Do? - Correct Answer Defend against the invasion of pathogens. Identify cancer cells or can become cancerous themselves Remove the body's litter by phagocytosis. Leave the circulation and go to the sites of invasion, inflammation and tissue damage. 5 types each with different roles in the immune system. The measurement of the total and differential WBC count is a part of all routine laboratory diagnostic evaluations. Two components? - Correct Answer It has two components..... First is a count of total number WBCs The other is the differential count, measuring the percentage of each type of leukocyte present in the specimen. List GRANULOCYTEs - Correct Answer Neutrophils Basophils Eosinophils AGRANULOCYTES - Correct Answer Lymphocytes Monocytes Avg WBC value in adults and children 2yrs - Correct Answer Adults and children 2yr: 5,000-10,000/mm3 (5-10) Neutrophil % of total WBC count - Correct Answer 55-70% Lymphocyte % of total WBC count - Correct Answer 20-40% Monocyte % of total WBC count - Correct Answer 2-8% Eosinophil % of total WBC count - Correct Answer 1-4% Basophil % of total WBC count - Correct Answer 0.5-1% Smallest WBC - Correct Answer Lymphocyte Largest WBC - Correct Answer M