OpenStax Microbiology Test Bank Chapter 20: Laboratory Analysis of the Immune Response
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Course
OpenStax Microbiology
Institution
OpenStax Microbiology
OpenStax Microbiology Test Bank
Chapter 20: Laboratory Analysis of the Immune Response
* = Correct answer Multiple Choice
1. Most antigens have how many epitopes?
A. none
B. one
C. two
D. more than two*
2. Which best describes monoclonal antibodies?
A. They are produced in living anima...
OpenStax Microbiology Test Bank
Chapter 20: Laboratory Analysis of the Immune Response
* = Correct answer
Multiple Choice
1. Most antigens have how many epitopes?
A. none
B. one
C. two
D. more than two*
2. Which best describes monoclonal antibodies?
A. They are produced in living animals only.
B. They are produced in tissue cultures, using B cells extracted from living animals.*
C. They are rarely used, so polyclonal antibodies are preferred.
D. They can be produced in either living animals or tissue cultures.
3. A hybridoma is which of the following?
A. a cancerous cell
B. a fusion of a B cell and a T cell
C. a fusion of a normal B cell and a myeloma cell*
D. a hybrid of two cancerous cells
4. Which is the correct term for a visible antigen-antibody complex?
A. epitope
B. heavy chain complex
C. hybridoma
D. precipitin*
5. Monoclonal antibodies bind to which of the following?
A. a single epitope*
B. a single hybridoma
C. multiple epitopes
D. variable numbers of epitopes
6. Double immunodiffusion is also known as which of the following?
A. flocculation assay
B. Ouchterlony assay*
C. precipitin ring test
D. radial immunodiffusion assay
, 7. Which technique is used to help view tissues, using microscopy?
A. electrophoresis
B. immunostaining*
C. lateral flow assays
D. western blotting
8. Which technique could be used to rapdly diagnose strep throat or mycoplasma pneumonia
by labeling bacteria with fluorescent monoclonal antibodies?
A. brightfield microscopy and ELISA techniques
B. fluorescence microscopy and direct fluorescent antibody techniques*
C. immunohistochemistry and immunostaining techniques in varying combinations
D. western blotting with chromogens or fluorogens
9. Which of the following describes antiserum?
A. a type of vaccine produced in the laboratory
B. antibodies obtained by exposing blood to an antigen in the lab
C. monoclonal antibodies obtained from the blood of an animal injected with an antigen
D. whole serum containing antibodies obtained from an animal exposed to an antigen*
10. When does an antibody test result in a false positive?
A. An individual tests as though she does not have the antigen even though she does.
B. An individual tests as though she has the antigen even though she does not.*
C. Antibodies bind to the antigen too strongly, causing an error in the testing protocol.
D. Variations in antibodies cause them to fail to bind to an antigen that is present.
11. Test sensitivity is defined as which of the following?
A. the probability that an individual will have a false-positive test result
B. the probability that an individual with an infection will test positive*
C. the probability that an individual with an infection will test negative
D. the probability that a test will detect multiple antigens simultaneously
12. Which of the following most commonly results from exposure to a single antigen?
A. A single antibody is produced that can respond to multiple antigens.
B. A single antibody is produced that is specific to that antigen.
C. Multiple antibodies are produced because antigens usually have multiple epitopes.
D. Multiple antibodies are produced to respond to a single epitope.*
13. When a particular test rarely produces false negatives, it has which of the following?
A. high sensitivity*
B. high specificity
C. low sensitivity
D. low utility
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