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NR565/ NR 565 FINAL EXAM ADVANCED PHARMACOLOGY 2024 EXAM COMPLETE 220 QUESTIONS WITH DETAILED VERIFIED ANSWERS (100% CORRECT) /ALREADY GRADED A+ CHAMBERLAIN $18.49
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NR565/ NR 565 FINAL EXAM ADVANCED PHARMACOLOGY 2024 EXAM COMPLETE 220 QUESTIONS WITH DETAILED VERIFIED ANSWERS (100% CORRECT) /ALREADY GRADED A+ CHAMBERLAIN
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NR565/ NR 565 FINAL EXAM ADVANCED PHARMACOLOGY 2024 EXAM COMPLETE 220 QUESTIONS WITH DETAILED VERIFIED ANSWERS (100% CORRECT) /ALREADY GRADED A+ CHAMBERLAIN

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  • April 11, 2024
  • 42
  • 2023/2024
  • Exam (elaborations)
  • Questions & answers

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  • NR 565 ADVANCED PHARMACOLOGY
  • NR 565 ADVANCED PHARMACOLOGY

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NR565/ NR 565 FINAL EXAM ADVANCED
PHARMACOLOGY 2024 EXAM COMPLETE 220
QUESTIONS WITH DETAILED VERIFIED ANSWERS
(100% CORRECT) /ALREADY GRADED A+
CHAMBERLAIN



Monitoring needs and intervals for Methimazole -
....ANSWER...Check CBC with differential if signs or
symptoms of infection. Check LFTs if signs or symptoms of
liver dysfunction.

High Risk Patients for Methimazole - ....ANSWER...Should
be avoided in the first trimester of pregnancy.

Methimazole Toxicity - ....ANSWER...Agranulocytosis is
the most dangerous toxicity.

PTU High Risk Warning - ....ANSWER...Carries a risk for
liver toxicity. Although rare, the FDA recommends against
using as a first-line treatment due to potential for hepatic
toxicity.

Effects of maternal hypothyroidism on offspring and
appropriate patient teaching related to need for treatment. -
....ANSWER...Can cause delay in mental development and
derangement of growth. In the absence of thyroid hormones,
the child develops a large and protruding tongue, potbelly,
and dwarfish stature. Development of the nervous system,
bones, teeth, and muscles is impaired.

,Congenital Hypothyroidism Treatment -
....ANSWER...requires replacement therapy with thyroid
hormones. If treatment is initiated within a few days of birth,
physical and mental development will be normal.

replacement therapy should continue for 3 years, after which
it should be stopped for 4 weeks to determine whether
thyroid deficiency is permanent or transient.


Patient Teaching for Levothyroxine - ....ANSWER...works
best if you take it on an empty stomach, 30 to 60 minutes
before breakfast.
take the medicine at the same time each day.

Ideal HbA1C goal for diabetic, non-pregnant adults -
....ANSWER...less than 7%.

HbA1C 8% - ....ANSWER...history of severe hypoglycemia,
limited life expectancy, or advanced microvascular or
macrovascular complications

HBA1C Value considered diagnostic of diabetes. -
....ANSWER...a value of 6.5% or greater

HbA1C Measuring Interval - ....ANSWER...every 3 months
until value is <7%; every 6 months thereafter

HbA1C Goal for Older Adults - ....ANSWER...<7.5% [58
mmol/mol]), while those with multiple coexisting chronic
illnesses, cognitive impairment, or functional dependence

,should have less stringent glycemic goals (such as A1C
<8.0-8.5% [64-69 mmol/mol]).

Criteria for the Diagnosis of Diabetes Mellitus -
....ANSWER...-Fasting plasma glucose ≥126 mg/dL
-Random plasma glucose ≥ 200 mg/dL plus symptoms of
diabetes
-Oral glucose tolerance test (OGTT): 2-h plasma glucose
≥200 mg/dLcor
-Hemoglobin A1c 6.5% or higher

T1DM Etiology and MOA - ....ANSWER...Autoimmune
process; Loss of pancreatic β cells;

T2DM Etiology and MOA - ....ANSWER...Unknown—but
there is a strong familial association, suggesting that
heredity is a risk factor; Insulin resistance and inappropriate
insulin secretion

the total daily dose (TDD) of insulin calculation -
....ANSWER...total weight of the patient in kilograms (kg),
multiplied by 0.6 units

Basal insulin replacement - ....ANSWER...50% of the total
daily insulin dose which replaces insulin from fasting
(overnight) and between meals.

Bolus insulin replacement - ....ANSWER...50% of the total
daily insulin dose and provides carbohydrate coverage and
high blood sugar correction.

Biguanides Drug Class - ....ANSWER...Metformin

, Metformin - ....ANSWER...Decreases glucose production by
the liver (glucogenesis), increases tissue response to insulin;

Decrease glucose absorption; Increase glucose uptake
drug of choice for initial therapy in most patients with type 2
diabetes

Metformin contraindications - ....ANSWER...renal disease,
acidosis from hepatic disease, alcoholics, or in patients with
hypoxia.

Metformin Major AE - ....ANSWER...Gastrointestinal (GI)
symptoms: decreased appetite, nausea, diarrhea
Lactic acidosis (rarely)

Sulfonylureas Prototype/MOA - ....ANSWER...Glyburide
(Prototype Drug)

-Promote insulin secretion by the pancreas; may also
increase tissue response to insulin;

-stimulate beta cells of the pancreas to secrete more insulin

Sulfonylureas AE - ....ANSWER...high risk of severe
hypoglycemia;
photosensitivity; therefore, patient education is needed
regarding sunscreen.
blood dyscrasias
weight gain.

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