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(MB) ASCP Practice Exam Questions & Detailed Answers 2024
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(MB) ASCP Practice Exam Questions & Detailed Answers 2024
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(MB) ASCP Practice Exam QuestioWhich of the following is not a component of a nucleotide?
Phosphate group
Anti-codon
Ribose sugar
Nitrogen base - correct answer Anti-codon
According to Chargaff's rule of base pairing, adenine pairs with: - correct answer Th
What genes would be screened in a breast cancer panel? - correct answer HER2, ER
Next Generation Sequencing uses: - correct answer Short sequence reads
Purines and pyrimidines differ from each other in that: - correct answer Purines hav
pyrimidines have one ring
The purines are:
Cytosine and uracil
Adenine and thymine
Thymine and cytosine
Adenine and guanine - correct answer Adenine and guanine
What is the rate of mutation per round of DNA replication?
1 in 1,000 base pairs
1 in 10,000 base pairs
1 in 1,000,000 base pairs
1 in 1,000,000,000 base pairs - correct answer 1 in 1,000,000,000 base pairs
,Find the palindrome in this restriction enzyme site: 5'-CTGCAG-3'?
5'-GAC
3'-GAC
3'-CTG
5'-GTC - correct answer 3'-GAC
A patient with impaired judgment, personality changes, signs of abnormal body mov
depression comes to the physician's office for a follow-up visit. The physician suspec
disorder may be the cause of those clinical manifestations. A blood specimen was th
clinical laboratory for mutation screening in the Huntington gene. Testing with stand
that patient has Huntington Disease, HD. Which of the following would be consistent
diagnosis?
25 CAG repeats in the Huntington gene
85 CAG repeats in the Huntington gene
25 CGA repeats in the Huntington gene
85 CGA repeats in the Huntington gene - correct answer 85 CAG repeats in the Hunt
Which two HPV types are responsible for most cases of cervical cancer?
16 and 18
31 and 59
16 and 58
44 and 59 - correct answer 16 and 18
Replication forks, known as origins of DNA replication, are created by this enzyme:
Ligase
Taq Polymerase
Primase
Helicase - correct answer Helicase
, RNA fragments - correct answer Okazaki fragments
What gene is measured following treatment with imatinib (Gleevec)?
FLT3
BCR/Abl
Jak2
MAPK - correct answer BCR/Abl
What is the rate of mammalian DNA replication?
500 nucleotides per second
100 nucleotides per second
50 nucleotides per second
10 nucleotides per second - correct answer 50 nucleotides per second
This polymerase is involved in "replicates mitochondrial DNA": - correct answer Pol
A patient with impaired judgment, personality changes, signs of abnormal body mov
depression comes to the physician's office for a follow-up visit. The physician suspec
disorder may be the cause of those clinical manifestations. A blood specimen was th
clinical laboratory for mutation screening in the Huntingtin gene. Which of these met
accomplish this task?
Methylation-specific PCR
Standard PCR
PFGE
RAPD PCR - correct answer Standard PCR
Which of the following storage options is optimal for storing isolated DNA for a perio
seven years?
22-25ºC
2-8ºC
-20ºC
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