Within 2-4 hours - ANSWhen should emetics be administered in order to be effective?
Apomorphine - ANSThis morphine derivative stimulates dopamine receptors in the CRTZ
which, in turn, activate the vomiting center in the medula.
Xylazine - ANSThis medication is used to induce vomiting in cats within 3-5 minutes.
Hydrogen peroxide - ANSWhat household chemical can be used in 3% solution to induce
vomiting by directly irritating the oropharynx and stomach lining.
Chlorpromazine and Prochlorperazine - ANSWhat 2 phenothiazine derivative centrally acting
anti-emetics act by blocking dopamine receptors in the CRTZ and may directly affect the
vomiting center.
Metoclopramide - ANSWhat procainamide derivative has both central and peripheral
antiemetic activities. It blocks dopamine receptors in the CRTZ and acts peripherally to
increase gastric contraction, speed gastric emptying, and strengthening cardiac sphincter
tone.
Antihistamines - ANSWhat type of anti-emetics are most effective in dogs and cats
experiencing motion sickness or inner ear problems. They also cause sedation.
1. Diphenhydramine (Benadryl)
2. Dimenhydrinate (Dramamine)
3. Meclizine - ANSName 3 antihistamines that can be used to treat motion sickness in dogs
and cats.
Ondansetron - ANSWhat 3 medication blocks serotonin receptors on vagal nerve terminals
and in the CRTZ? It is particularly effective during chemotherapy.
Maropitant citrate (Cerenia) - ANSWhat very common antiemetic blocks NK-1 receptors in
the CRTZ?
1. H2 receptor antagonists
2. Proton pump inhibitors
3. Antacids
4. Gastromucosal protectants
5. Prostaglandin E1 analogues - ANSWhat 5 classes of drug are used to treat gastric ulcers?
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