100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
N5315 Advanced Pathophysiology Quiz #2 Questions With Complete Solutions $12.99   Add to cart

Exam (elaborations)

N5315 Advanced Pathophysiology Quiz #2 Questions With Complete Solutions

1 review
 7 views  0 purchase

N5315 Advanced Pathophysiology Quiz #2 Questions With Complete Solutions

Preview 3 out of 21  pages

  • April 18, 2024
  • 21
  • 2023/2024
  • Exam (elaborations)
  • Questions & answers
All documents for this subject (18)

1  review

review-writer-avatar

By: Fordenken • 4 months ago

avatar-seller
QUALITYGRADES
N5315 Test 2 Questions with Complete Solutions

HIV EIA (3rd generation immunoassay) - can use urine, saliva, or serum (most

accurate), need to wait until 12 weeks post exposure to see antibodies, >99% accurate

4th generation immunoassay- "gold standard"

measures P24 antigen

can test 10 days post exposure



Mast cell - Cellular bags of granules located in loose connective tisssue close to blood

vessels. Activation initiates inflammatory process.



Histamine - Causes vasodilation, increases vascular permeability, increases blood flow

to the site of injury- causes erythema and swelling.



Cytokines - Soluble factors that contribute to the regulation of innate or adaptive

resistance by affecting other neighboring cells. Can be pro-inflammatory or anti-

inflammatory. Can react quickly or be more delayed.



Leukotrines - Released when mast cells degranulate, prolong the inflammatory process.

Cause vasodilation, attract neutrophils, monocytes, and eosinophils.target of inhibition

for singular.

,Prostaglandins - Released when mast cells degranulate, are produced by the

arachidonic pathway. Cause vasodilation, platelet aggregation at site of injury, pain, and

fever.



Chemotactic factors - Biochemical substance that attracts leukocyte to the site of

inflammation



Neutrophils - Predominant leukocyte at work during the early stages of acute

inflammation



Monocytes - Become macrophages when entering the tissue, responsible for presenting

antigens to the CD4 cell which triggers T-cell immunity and B-cell immunity.

Releases additional cytokines IL1, IL6, TNF.



Cytokine IL1 function - Causes fever, activates phagocytes & lymphocytes and also

increases the release of IL6a



Cytokine IL6 function - Stimulates production of acute phase reactants and promotes

growth and stimulation of RBCs



Cytokine TNF function - Causes fever, increases synthesis of proinflammatory proteins

by liver, causes muscle wasting, induces thrombosis

, Cytokine growth factor function - Promotes production and maturation of neutrophils



Complement - Functions include bacterial lysis, vasodilation and increased vascular

permeability, triggers mast cell degranulation, chemotaxis, and opsonization.



Kinin - Converted to bradykinin which is responsible for pain and chemotaxis, and it

increases vascular permeability and vasodilation.



Coagulation cascade - Factor XII activates kinin. Function is to form fibrin mesh to stop

bleeding and trap micro organisms.



COX1 - Prostaglandin of arachidonic pathway. Provides gastroprotection, platelet

aggregation, fluid/electrolyte balance



COX2 - Prostaglandin of arachidonic pathway. Responsible for pain, fever, renal

protection, tissue repair, reproduction development.



COX2 inhibitors- clinical implications - Protect gastric mucosa- prevent ulcers and

bleeding. Removed from market r/t cardiac events except for Celebrex. Can impair renal

function , monitor labs.



Arachidonic pathway purpose - Synthesis of prostaglandins

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller QUALITYGRADES. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $12.99. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

71947 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$12.99
  • (1)
  Add to cart