SBB math/genetics Exam Questions With Correct Answers

Mendel - Answer-random/independent auto/dom - Answer-every generation/half children/equal male v female auto/recessive - Answer-siblings/no parents/ 1/4 kids/ equal male v female sex-linked dominant - Answer-X chromosome (homo all/hetero half) sex-linked recessive - Answer-X chromosome (higher men-from women carriers) Y-linked - Answer-father to son (all) chromosome 1 antigens - Answer-Rh/Duffy/Sc/Cr/Kn chromosome 9 antigens - Answer-ABO chromosome 19 - Answer-Lu/Le/Lw/Hh/Se Hardy-Weinberg equation - Answer-(p+q)squared= p squared + 2pq+q squared = 1 2 alleles of Hardy-weinberg - Answer-p+q=1 or q=1-p expanded Hardy-Weinberg - Answer-p squared + 2p(1-p) + (1-p) squared = 1 patient with anti-E and anti-K (30 E+) (10 K+) find negs - Answer-70 E- 90 K- = 63% neg for both #unit needed divided by #1Cryoprecipitate needed when given HCT/Fibrinogen/weight (/by 2.2 for kg) - Answer-1. Kgx75 [1-HCT) for plasma volume 2. 150 (fibrinogen we want)- fibrinogen we have x plasma vol/ (all divided by 100) 3. divide by 250 a bag Corrected Platelet count increment (CCI) when given weight (/by 2.2 for kg)/height/before platelets/after platelets/and amount transfused - Answer-1. HTxWT/3600 then square root 2. platelet after-platelet before 3. #1 x #2 / amount transfused (check exponents) Fetal bleed kleihauer betke given % fetal bleed- How much blood volume in hemorrhage and Rhig - Answer-% X 50 (dosage)/ 30 (round up for vials) autologous unit can be drawn given weight (under weight) - Answer-450 (WB av) x person weight / 110 (Weight av) coag needed to remove since under weight - Answer-63 (av coag) x person weight/ 110 (weight av) FTE needed - Answer-1. weeks worked (sub off) x 40 x productivity (45 min) 2. annual workload / #1 volume of plasma for 1 vol plasma exchange given weight (/2.2 if lbs) and HCT - Answer-weight (kg) x 75 x (1-HCT % 0.)= 1 vol platelet yield when given platelet count/amount WB donated/prepared platelet concentrate - Answerplatelet concentrate / (plt count x donated WB mls x 1000) Harvey Weinberg #1 - Answer-84% D + and 16% are d (D=) p=D q=d find p2 (DD) and 2pq (Dd) and ddHarvey Weinberg #2 - Answer-Autosomal dominant (p2 + 2pq) in 51% pop- find gene frequency p=Gene freq of dominant q=Gene freq of recessive p2 + 2pq+ q2 =1 p+q=1 Harvey Weinberg #3 - Answer-27% Jka+ need GF of Jka and GF of Jkb and Jka+b+ Harvey Weinberg #4 - Answer-3 genes p+q+r=1 p2 +2pq+q2+2qr+r2+2pr= 1 p2=AA, q2=BB, r2=OO 28=AA,AO 53=OO 15=BO,BB 4=AB find GF of A,B,O Genotype for child? a.R0r R1R2 rr' rr - Answer-Dad D-C-E-c+e+ mom D+C+E+c+e+ dad's dad D+D+E-c+e+ dad's mom D+C-E-c+e+ mom's mom D-C+E-c+e+ 200lb HCT 38% Fibrinogen 95- like it to be 150 How many bags cryo? - Answer160 cm HT 82 kg WT transfused 6X10'11 before 15,000 1hr= 45,000 Corrected platelet count increment CCI? - Answer- 1.3% fetal bleed est. blood volume? how much Rhg? - Answerunderweight 73 lbs donated WB autologous how much blood can be drawn? - AnswerFTEs vacation 2 weeks sick 5 days holidays 6 days cont ed 4 days productivity 75% workload 400,000 min How many FTEs? - Answer