ALU 301 Exam study Guide |Questions with Complete
Solutions
Cells that can recognize altered surface molecules on mutated host cells add "foreign" and move to
destroy the cell that carries them are:
1. complements
2. receptors
3. natural killers
4. mediators
natural killers
All of the following are common examples of autoimmune disease EXCEPT:
1. Hashimoto's thyroiditis
2. systemic lupus erythema toss
3. Grave's thyroid disease
4. poliomyelitis
poliomyelitus
Which of the following statements regarding serum immunoglobulin levels is/are correct?
A. Monoclonal gammopathy is a risk for transformation into multiple myeloma
B. Polyclonal gammopathy is frequently associated with chronic infections
C. Low serum globulin can indicate a primary immune deficiency
A, B. & C are correct
A. Monoclonal gammopathy is a risk for transformation into multiple myeloma
B. Polyclonal gammopathy is frequently associated with chronic infections
C. Low serum globulin can indicate a primary immune deficiency
The type of immune cell that differentiates in the bone marrow is:
1. T-lymphocytes
2. Helper T-cells
3. natural killer cells
4. B-lymphocytes
B-lymphocytes
Which of the following statements regarding T-lymphocytes is/are correct:
A. One type is cytotoxic T-cells
B. They eliminate infected cells
C. They provide immunity by production of antibodies
A and B only are correct
A. One type is cytotoxic T-cells
B. They eliminate infected cells
Describe the five cell typed present in the white blood cell count and how are they impacted by
various types of infections.
neutrophils, monocytes, eosinophils, basophil, lymphocyte
,Describe the difference between immunotherapy and immunosuppression.
immunotherapy uses the immune system to focus treatment of a specific pathogen or targeted cell.
immunosuppression is caused by corticosteroids and immunopressive medications.
Describe common variable immunodeficiency and the ways it affects the immune system.
chronic pulmonary infection and low globulin levels.
chronic sinus infections, pulmonary infections leading to bronchitis, diarrhea, RA, and gluten sensitive
Malabsorption
The mainstay of treatment for acute mild to moderate ulcerative colitis is:
1. Proton pump inhibitors
2. 5-aminosalicylate compounds
3. immunomodulators
4. biologic agents
2. 5-aminosalicylate compounds
All of the following statements regarding Crohn's disease are correct EXCEPT:
1. It involves inflammation of all layers of the bowel wall
2. It can involve nearby lymph nixes
3. The most common presenting symptom is a fistula
4. Skip lesions are often seen on endoscopy
3. The most common presenting symptom is a fistula
Which of the following statements regarding the cancer risk with ulcerative colitis is/are correct?
A. The prenalignsnt lesion is usually a polyp
B. The duration of disease is a risk factor
C. A colectomy is recommended when dysplasia is present
B and C only are correct
B. The duration of disease is a risk factor
C. A colectomy is recommended when dysplasia is present
Deep linear ulceration that are separated by normal mucosa seen on imaging are:
1. skip lessons
2. bowel ischemia
3. celiac sprue
4. diverticulitis
1. skip lesions
Ulcerative colitis disease severity is determined by:
1. age
2. recurrence
3. Endoscopy
,4. laboratory findings
3. endoscopy
All of the following statements regarding ulcerative colitis are correct EXCEPT:
1. It involves inflammation of all layers of the colon wall
2. it manifests only in the colon
3. the most common presenting symptom is,a,rectal bleeding
4. physical findings can be nonspecific
1. It involves inflammation of all layers of the colon wall
Factors that can contribute to the development of inflammatory bowel diseases include which of the
following?
A. history of alcoholism
B. generic susceptibility
C. environmental factors
B and C only at correct
B. generic susceptibility
C. environmental factors
Serologic markers used in the diagnosis of Inflammatory bowl disease include:
A. Aloha-fetoprotein
B perinuclear anti neutrophil cytoplasmic antibodies
C. anti-saccharomyces cere visited Antibodies
B and C only are correct
B perinuclear anti neutrophil cytoplasmic antibodies
C. anti-saccharomyces cere visited Antibodies
The triad of positive rheumatoid factor, enlarged spleen, and neutropenia is:
1. Caplan's syndrome
2. Felty's syndrome
3. Sjogren's syndrome
4. Still's disease
2. Felty's syndrome
All of the following statements regarding laboratory testing on individuals with rheumatoid arthritis
(RA) are correct EXCEPT:
1. Globulins are often elevated
2. Cholesterol can be low in late-stage disease
3. The inflammatory process can elevate HDL
4. Low albumin is a poor prognostic indicator
3. The inflammatory process can elevate HDL
The joints commonly affected by RA include all of the following EXCEPT:
1. elbows
2. knees
3. shoulders
4. hips
, 4. hips
All of the following laboratory tests are commonly used for the diagnosis and monitoring of
rheumatoid arthritis EXCEPT:
1. gamma-glutamyl transferase (GGT)
2. rheumatoid factor (RF)
3. anti-cyclic citrullinated peptide (anti-CCP)
4. C-reactive protein (CRP)
1. gamma-glutamyl transferase (GGT)
The hallmark of current therapy for rheumatoid arthritis is the use of:
1. non-steroidal anti-inflammatory drugs (NSAIDS)
2. cyclooxygenase inhibitors (COX)
3. disease modifying anti-rheumatic drugs (DMARDS)
4. corticosteroids
3. disease modifying anti-rheumatic drugs (DMARDS)
A round calcified mass of scar tissue seen on a chest x-ray can be associated with a history of:
1. atelectasis
2. pneumothorax
3. histoplasmosis
4. pulmonary embolism
3. histoplasmosis
Bacteria can be classified in all of the following ways EXCEPT:
1. number of cells
2. structural characteristics
3. reaction to staining
4. need for oxygen
1. number of cells
Kawasaki's disease can cause which of the following?
A. coronary aneurysms
B. chronic hepatitis
C. ulcerative colitis
A. Coronary aneurysms
Increased mortality from encephalitis is often associated with:
A. organ failure
B. herniation of the brain
C. increased intracranial pressure
A. organ failure
B. herniation of the brain
C. increased intracranial pressure
Which of the following statements regarding viruses is/are accurate?
A. They can contain DNA, RNA or both
B. They use the reproductive capacity of the host to replicate
C. They do no have a cellular structure
B. They use the reproductive capacity of the host to replicate
Solutions
Cells that can recognize altered surface molecules on mutated host cells add "foreign" and move to
destroy the cell that carries them are:
1. complements
2. receptors
3. natural killers
4. mediators
natural killers
All of the following are common examples of autoimmune disease EXCEPT:
1. Hashimoto's thyroiditis
2. systemic lupus erythema toss
3. Grave's thyroid disease
4. poliomyelitis
poliomyelitus
Which of the following statements regarding serum immunoglobulin levels is/are correct?
A. Monoclonal gammopathy is a risk for transformation into multiple myeloma
B. Polyclonal gammopathy is frequently associated with chronic infections
C. Low serum globulin can indicate a primary immune deficiency
A, B. & C are correct
A. Monoclonal gammopathy is a risk for transformation into multiple myeloma
B. Polyclonal gammopathy is frequently associated with chronic infections
C. Low serum globulin can indicate a primary immune deficiency
The type of immune cell that differentiates in the bone marrow is:
1. T-lymphocytes
2. Helper T-cells
3. natural killer cells
4. B-lymphocytes
B-lymphocytes
Which of the following statements regarding T-lymphocytes is/are correct:
A. One type is cytotoxic T-cells
B. They eliminate infected cells
C. They provide immunity by production of antibodies
A and B only are correct
A. One type is cytotoxic T-cells
B. They eliminate infected cells
Describe the five cell typed present in the white blood cell count and how are they impacted by
various types of infections.
neutrophils, monocytes, eosinophils, basophil, lymphocyte
,Describe the difference between immunotherapy and immunosuppression.
immunotherapy uses the immune system to focus treatment of a specific pathogen or targeted cell.
immunosuppression is caused by corticosteroids and immunopressive medications.
Describe common variable immunodeficiency and the ways it affects the immune system.
chronic pulmonary infection and low globulin levels.
chronic sinus infections, pulmonary infections leading to bronchitis, diarrhea, RA, and gluten sensitive
Malabsorption
The mainstay of treatment for acute mild to moderate ulcerative colitis is:
1. Proton pump inhibitors
2. 5-aminosalicylate compounds
3. immunomodulators
4. biologic agents
2. 5-aminosalicylate compounds
All of the following statements regarding Crohn's disease are correct EXCEPT:
1. It involves inflammation of all layers of the bowel wall
2. It can involve nearby lymph nixes
3. The most common presenting symptom is a fistula
4. Skip lesions are often seen on endoscopy
3. The most common presenting symptom is a fistula
Which of the following statements regarding the cancer risk with ulcerative colitis is/are correct?
A. The prenalignsnt lesion is usually a polyp
B. The duration of disease is a risk factor
C. A colectomy is recommended when dysplasia is present
B and C only are correct
B. The duration of disease is a risk factor
C. A colectomy is recommended when dysplasia is present
Deep linear ulceration that are separated by normal mucosa seen on imaging are:
1. skip lessons
2. bowel ischemia
3. celiac sprue
4. diverticulitis
1. skip lesions
Ulcerative colitis disease severity is determined by:
1. age
2. recurrence
3. Endoscopy
,4. laboratory findings
3. endoscopy
All of the following statements regarding ulcerative colitis are correct EXCEPT:
1. It involves inflammation of all layers of the colon wall
2. it manifests only in the colon
3. the most common presenting symptom is,a,rectal bleeding
4. physical findings can be nonspecific
1. It involves inflammation of all layers of the colon wall
Factors that can contribute to the development of inflammatory bowel diseases include which of the
following?
A. history of alcoholism
B. generic susceptibility
C. environmental factors
B and C only at correct
B. generic susceptibility
C. environmental factors
Serologic markers used in the diagnosis of Inflammatory bowl disease include:
A. Aloha-fetoprotein
B perinuclear anti neutrophil cytoplasmic antibodies
C. anti-saccharomyces cere visited Antibodies
B and C only are correct
B perinuclear anti neutrophil cytoplasmic antibodies
C. anti-saccharomyces cere visited Antibodies
The triad of positive rheumatoid factor, enlarged spleen, and neutropenia is:
1. Caplan's syndrome
2. Felty's syndrome
3. Sjogren's syndrome
4. Still's disease
2. Felty's syndrome
All of the following statements regarding laboratory testing on individuals with rheumatoid arthritis
(RA) are correct EXCEPT:
1. Globulins are often elevated
2. Cholesterol can be low in late-stage disease
3. The inflammatory process can elevate HDL
4. Low albumin is a poor prognostic indicator
3. The inflammatory process can elevate HDL
The joints commonly affected by RA include all of the following EXCEPT:
1. elbows
2. knees
3. shoulders
4. hips
, 4. hips
All of the following laboratory tests are commonly used for the diagnosis and monitoring of
rheumatoid arthritis EXCEPT:
1. gamma-glutamyl transferase (GGT)
2. rheumatoid factor (RF)
3. anti-cyclic citrullinated peptide (anti-CCP)
4. C-reactive protein (CRP)
1. gamma-glutamyl transferase (GGT)
The hallmark of current therapy for rheumatoid arthritis is the use of:
1. non-steroidal anti-inflammatory drugs (NSAIDS)
2. cyclooxygenase inhibitors (COX)
3. disease modifying anti-rheumatic drugs (DMARDS)
4. corticosteroids
3. disease modifying anti-rheumatic drugs (DMARDS)
A round calcified mass of scar tissue seen on a chest x-ray can be associated with a history of:
1. atelectasis
2. pneumothorax
3. histoplasmosis
4. pulmonary embolism
3. histoplasmosis
Bacteria can be classified in all of the following ways EXCEPT:
1. number of cells
2. structural characteristics
3. reaction to staining
4. need for oxygen
1. number of cells
Kawasaki's disease can cause which of the following?
A. coronary aneurysms
B. chronic hepatitis
C. ulcerative colitis
A. Coronary aneurysms
Increased mortality from encephalitis is often associated with:
A. organ failure
B. herniation of the brain
C. increased intracranial pressure
A. organ failure
B. herniation of the brain
C. increased intracranial pressure
Which of the following statements regarding viruses is/are accurate?
A. They can contain DNA, RNA or both
B. They use the reproductive capacity of the host to replicate
C. They do no have a cellular structure
B. They use the reproductive capacity of the host to replicate
