MMSC 491 Exam 2
The term phenotype can be applied to a wide range of maifestations. Which of the following protperties, if any do not constitute a phenotypic manifestation - ANS>The sequance of a persons beta globin gene
Which, if any, of the following is incorrect? when used in human genetic
- ANS>Incorrect: The term dominant and recessive apply equally to allels and phenotypes
Correct:
- Dominant describes a phenotype that is manifestated in the heterozygotem that is, the phenotype is attributed to just a single allele
-Recessive describes a phenotype that is manifest as a result of the combined effects of boht alleles at a locus
-The AB blood group is an example of a co-dominant phenotype
With respect to autosomal recessive inheritance, which, if any, of the following statements is incorrect - ANS>Incorrect: Heterozygotes are always asymptomatic carriers
Correct: -Affected individuals normally have unaffected parents
-for unaffected parents who have previously affected child, there is a 1 in 4 risk of having an affected child on each occasion that they produce a new child
-Some affected individuals have alleles with idnetical pathogenic mutations but many have two different mutant alleles and are described as compund heterozygotes
With respect to X-chromsome inactivation in females, which, if any of the following statements is incorrect - ANS>Incorrect: The process involves epeigentic silencing of each gene on one of the two x chromsomes, either the maternal X chromsome or the paternal X chromsome
Correct
-X inactiavation first occurs in the preimplantation female mammalian embryo
-One of the two X chromsomes in each diploid cell of a normal women is randomly selected to undergo X-inactation and becomes highly condensed
-Once the decision is made to inactavate a paternal X or the maternal X in a cell, all descendant cells will continue with that pattern of X-
inactivation
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