CPPS 306 Midterm Exam Questions with Answers

Used to treat Parkinson's Disease -Crosses the Blood Brain Barrier (unlike dopamine) and is decarboxylated to dopamine -Given with a peripheral decarboxylase inhibitor to permit lower dose and to lower nausea and vomiting side effects -Side effects: orthostatic hypotension, sedation, confusion, hallucinations, psychosis -Gold standard of treatmentLevo-dopa Give with levodopa (Parkinsons) Inhibits DOPA-decarboxylase in periphery--increased levodopa in CNSCarbidopa Parkinsons peripheral COMT inhibitorEntacapone Parkinsons Peripheral COMT inhibitorTolcapone Parkinsons MAO-B inhibitorSelegiline MAO-B inhibitor used in parkinsons (just like selegeline)Rasagaline Parkinson's Dopamine agonistBromocriptine Parkinson's Dopamine agonistPramipexole Dopamine agonist (Parkinson's)Ropinirole Dopamine agonist (Parkinson's)Rotigotine Anticholinergic agent (Parkinson's)Benztropine Anticholinergic agent (Parkinson's)Trihexyphenidyl typical antipsychotic high potency