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CRNI: chemotherapy questions and answers with solution 2024
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CRNI: chemotherapy questions and answers with solution 2024
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CRNI: chemotherapy questions and answers with solution 2024 Most common types of cancer for men - ANSWER Lung, prostate, colon Most common types of cancer for women - ANSWER Lung, breast, colon Goals of chemotherapy - ANSWER cure, control, palliative vesicant - ANSWER substance that can cause tissue necrosis and damage Extravasation - ANSWER escape of vesicant fluid from a blood vessel into surrounding tissue that can lead to tissue necrosis and sloughing irritant - ANSWER a substance that causes inflammation or discomfort but no necrosis adjuvant therapy - ANSWER Agent administered in conjunction with another treatment combination therapy - ANSWER The administration of two or more chemo medications simultaneously to achieve better outcomes, use less of each chemo agent to achieve desired results, reduce side effects, reduce resistance to agents Combination chemotherapy protocols: CHOP - ANSWER For non -hodgkins lymphoma; Cyclophosphamide, doxorubicin, vincristine, & prednisone Combination chemotherapy protocols: FAM - ANSWER For pancreatic ca; fluorouracil, doxorubicin, & mitomycin Combination chemotherapy protocol: MOP P - ANSWER For lymphoma, Hodgkin's disease. Mechlorethanine, vincristine, procarbazine, & prednisone. Combination chemotherapy protocol: VAD - ANSWER For multiple myeloma. vincristine, doxorubicin, & dexamethasone. Vinca Plant Alkaloids (M -phase cell cyc le specific) - ANSWER Vincristine, vinblastine, etoposide, teniposide Antimetabolites (s -phase cell cycle specific) - ANSWER 5 -Fu, methotrexate Nitrosoureas - ANSWER Only agent that will cross the blood brain barrier Methotrexate side effects - ANSWER S tomatitis, nephrotoxicity, ulcers in mouth Use of leucovorin 12 -24 hours after this drug as antidote to bone marrow toxicity, to 'rescue' bone marrow - ANSWER Methotrexate This drug may cause 'radiation recall' and/or photosensitivity where an area of pr ecious radiation exposure will turn red - ANSWER Methotrexate This agent may only be administered intraarterially - ANSWER Floxuridine May be given IV or intrathecal, side effects occurring 6 -12 hrs after administration - ANSWER Cytarabine DO NOT give a llopurinol with this chemo agent - ANSWER Fluorouracil aka 5 FU Side effects of fluorouracil/ 5 FU - ANSWER Charcoal gray/hyper pigmentation of veins and nails, diarrhea, paresthesia due to peripheral nerve damage This drug must be administered within 1 hour and side effects include pancytopenia - ANSWER GemcitabineThe benefits of buying summaries with Stuvia:
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