CDE EXAM QUESTIONS AND ANSWERS

CDE EXAM QUESTIONS AND ANSWERS Sulfonylureas contraindications - ANS DKA, Type 1 diabetes, Hypersensitivity Sulfonylureas Precautions - ANS hypoglycemia, hepatic insufficiency Sulfonylurea monitoring - ANS renal and hepatic function Sulfonylureas causes sensitivity to ? - ANS sunlight so wear sunscreen Sulfonylureas cause what disorder - ANS SIADH, thrombocytopenia, abnormal LFT's, agranulocytosis, Hemolytic anemia, butamide How is glipizide(glucotrol) taken - ANS on an empty stomach What are the Meglitinides - ANS Repaglinide(Prandin), Nateglinide (Starlix) How do Prandin and Starlix(Meglitinides) Work - ANS Increase insulin secretion from the Pancreas-considered secretagogues Do the meglitinides (prandin and Starlix) mechanism of action shorter or longer that the sulfonlylureas - ANS shorter Stalix(Nateglinide) insuling release - ANS Post-Prandial insulin release Post-Prandial - ANS After meals Repaglinide - ANS Prandin Never mix Meglinitides( Nateglinide or Repaglinide) with what drug class - ANS Sulfonlynureas Can you use Nateglinides(Starlix) or Repaglinides(Prandin)(Meglinitides) in with sulfonylureas? - ANS No When do you take Nateglinides or Repagelindes - ANS just before meals Repaglinide(prandin) Frequency - ANS TID 15- 30 min before meal be careful in renal patients Nateglinide(Starlix) dosage adjustment in renal patients - ANS none needed How is Nateglinide take - ANS TID 1-30 minutes before meals where is Repaglinide absorbed(Prandin) - ANS GI tract and Liver Nateglinide take with - ANS high fat meal Meglitinides Contraindications - ANS Type 1, DKA, Infection, surgery, Trauma Precautions with Meglitinides - ANS Hepatic impairment, Elderly, malnourished, adrenal insufficiency Meglitinides Adver