PATHOPHYSIOLOGY 370 MIDTERM WITH 100% CORRECT ANSWERS ALREADY GRADED A+

A serious complication of deep vein thrombosis A pulmonary embolus Venous obstruction leads to edema because it ___________ pressure Increases capillary hydrostatic A cause of thrombocytopenia includes chemotherapy Which is not a manifestation of acute arterial obstruction? Purpura Risk factors for atherosclerosis include Hyperlipidemia A laboratory test finding helpful in confirming the diagnosis of iron deficiency anemia is Elevated total iron-binding capacity The major cause of death from leukemic disease is Infection Pernicious anemia is caused by a lack of Intrinsic factor Activation of intrinsic pathway of coagulation is initiated by Tissue thromboplastin Tissues are able to auto-regulate their rate of blood flow by controlling Vascular resistance A three-year-old boy who exhibits prolonged bleeding after minor trauma and a prolonged aPTT, but a normal platelet count, is likely to be diagnosed with Hemophilia Blood flow throughout the periphery is regulated by The autonomic nervous system Patients with immunodeficiency disorders are usually first identified because they Develop recurrent infections True or False: The anemia resulting from a deficiency of either vitamin B 12(cobalamin) or folate is caused by a disruption in DNA synthesis of the blast cells in the bone marrow that produces very large abnormal bone marrow cells called megaloblasts True Which condition is associated with an elevated reticulocyte count? hemolytic anemia What laboratory finding is usually found in aplastic anemia? Pancytopenia Which disorder is considered a primary immunodeficiency disease? HIV/AIDS A patient is diagnosed with a tortuous blood vessel of the right hand that bleeds spontaneously. This patient presents with Telangiectasia What characteristic is indicative of hemolytic anemia? Jaundice The movement of blood through the vascular system as opposed by the force of Resistance Autologous cell transplantation is a procedure in which Stem cells are harvested from the patient and then returned to the same patient Which causes vasoconstriction? Norepinephrine The hypersensitivity reaction that does not involve antibody production is type IV Disseminated intravascular coagulation may be treated with heparin therapy to Inhibit clotting factor consumption The final step in clot formation is: Clot retraction Which condition enhances lymphatic flow? Increased interstitial fluid colloid osmotic pressure A low mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular volume (MCV) are characteristic of which type of anemia? Iron deficiency True or false: vaccination for pneumococcal pneumonia should be performed before one year of age in patients with sickle cell anemia False An increase in hemoglobin affinity for oxygen occurs with Shift to the left Strengthen the bond between oxygen hemoglobin is known as the Oxygen-hemoglobin affinity The primary source of erythropoietin is provided by the Kidney Red blood cells differ from other cell types in the body because they Have no cytoplasmic organelles True or False: The only known curative treatment for CML is allogenic bone marrow transplant Tatian from a suitable donor True Which type of leukemia primarily affects children? ALL (acute lymphoid leukemia) The most effective therapy for anemia associated with kidney failure is erythropoietin administration. The primary effect or cell of the type one hypersensitivity response is Mast cells Which disorder is associated with a type III hypersensitivity mechanism of injury? systemic lupus erythematosus The goal of long term heparin for the management of a deep vein thrombosis is to Prevent further clot formation Widespread activation of clotting cascade secondary to massive trauma is called Disseminated intravascular coagulation (DIC) The megakaryocyte is a precursor to platelets Which genetic aspect is associated with the development of auto immune diseases? MHC genes Which of the following disorders displays these characteristics? failure to remove antigen antibody complexes Is not tissue specific Includes antibodies Occurs over several hours or days Also called immune complex reaction Type III hypersensitivity DiGeorge Syndrome is deficiency of T cells. The aplastic or hypoplastic thymus is unable to assist in the maturation of T cells. Therefore T cells are deficient And example of neoplasms from the myeloid lineage include alterations in Granulocytes