Exam (elaborations)
IMMUNOLOGY KUBY CHAPTER 4
- Course
- Institution
IMMUNOLOGY KUBY CHAPTER 4
[Show more]
Seller
Follow
modockochieng06
Content preview
IMMUNOLOGY KUBY CHAPTER 4Allotype - ANS-an antibody of a given class having certain molecular sites shared by
only some members of a species and therefore acting as an antigen to other members
of the same species.
Antigen - ANS-Any substance (usually foreign) that binds specifically to an antibody or a
T-cell receptor; often is used as a synonym for immunogen.
Dendritic cells - ANS-are antigen-presenting cells of the immune system. Their main
function is to process antigen material and present it on the cell surface to the T cells of
the immune system. They act as messengers between the innate and the adaptive
immune
Epitope - ANS-The portion of an antigen that is recognized and bound by an antibody or
TCR/MHC combination; also called antigenic determinant.
factors that determine immunogenicity - ANS-1) chemical Composition and
Heterogeneity:
2) Size
(3) foreignness:
(4 Susceptibility to Antigen Processing and Presentation
(5)Degradability and Solubility
How are the T-cell receptors and B-cell receptors similar? - ANS-Although B cells and T
cells recognize foreign molecules in distinct fashions, the receptor molecules they use
for this task are very similar in structure. These T-cell receptors (TCRs) are related to
immunoglobulins both in their protein structure—having both V and C regions—and in
the genetic mechanism that produces their great variability.
How does the primary function of T-cell receptors differ from that of B-cell receptors? -
ANS-The antigen-recognition molecules of T cells are made solely as membrane-bound
proteins, which are associated with an intracellular signaling complex and function only
to signal T cells for activation.
How is the structure of an antibodies? - ANS-Antibody molecules are roughly Y-shaped
molecules consisting of three equal-sized portions connected by a flexible tether. The
ends of the two arms of the Y—the V regions—vary in their detailed structure between
different antibody molecules. These are involved in antigen binding. The stem of the
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller modockochieng06. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $7.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
77529 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now