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AII Exam 2 - Yves (4, 9, 31, 33)
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AII Exam 2 - Yves (4, 9, 31, 33)
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AII Exam 2 - Yves (4, 9, 31, 33)A positive tuberculin test is an example of a type ____ hypersensitivity immune
response. - ANS-IV
After his citizenship ceremony in a super old building downtown Portland. The patient
presents with symptoms of wheezing, dyspnea, and cough two days later. He says it is
worse at night or in the early morning. On physical examination you note prolonged
expiration and diffuse wheezes. As a SmartyPance PA, you tell them what? - ANS-You
are suffering from allergic Asthma young man.
Anaphylaxis, angioedema, and urticaria are examples of type ____ hypersensitivity
immune responses. - ANS-I
any undesirable & unintended response elicited by a drug reminds me of? -
ANS-Adverse Drugs Reaction (ADRs)
Delayed hypersensitivity is a type ____ reaction mediated by _____. Immediate
hypersensitivity is a type ___ reaction mediated by _____. - ANS-IV; T Cells; I; IgE,
mast cells, and eosinophils.
Distinguish allergic rhinitis from vasomotor rhinitis. Use the following word salad.
Seasonal variation, Vidian nerve, conjunctival erythema and excessive tearing,
Symptoms are often triggered by nasal stimuli - ANS-Allergic rhinitis is usually
persistent but may show seasonal variation. Nasal symptoms are often accompanied by
eye irritation, pruritus, conjunctival erythema and excessive tearing.
Vasomotor rhinitis on the other hand is caused by increased sensitivity of the vidian
nerve and is a common cause of clear rhinorrhea in the elderly. Symptoms are often
triggered by nasal stimuli such as warm/cold air, odors or scents, light or particulate
matter.
Dose dependent. Predictable. More common. Type? - ANS-Type A drug reaction
Drug-induced hemolytic anemia is an example of a type ____ hypersensitivity immune
response. - ANS-II
Immunologic drug reactions / drug allergy is _____________mediated. - ANS-Immune
mediated. can be mediated by IgE (minutes to hours), IgG, or T Cells (days to weeks)
, Serum sickness is an example of a type _____ hypersensitivity immune response. -
ANS-III
T/F Topical nasal decongestants should be used for more than a few days to have a
true effect. Withdrawal of the drug after prolonged use leads to rhinitis medicamentosa -
an addictive need for continuous usage. - ANS-FALSE... Withdrawal of the drug after
prolonged use leads to rhinitis medicamentosa - an addictive need for continuous
usage.
Test - ANS-Test
Test - ANS-Test
This form of drug reaction results from mechanisms not currently understood and this
drug rxn is unpredictable and different from the known drug toxicities & are relatively
rare. - ANS-Idiosyncratic drug reactions
Type I hypersensitivity triggers _____ antibodies to bind to _____ cells, which release
________. - ANS-IgE, Mast. Inflammatory mediators (histamine, eicosanoids,
chemokines)
What are some examples of pathology caused by Type II hypersensitivity mechanism
(3)? - ANS--Immune hemolytic anemia
-Rh hemolytic disease in newborns
-Autoimmune hyperthyroidism (thyroid-stimulating antibodies stimulate thyroid tissue)
What are some examples of pathology caused by Type III hypersensitivity mechanisms
(4)? - ANS--Cutaneous arthus reaction
-Systemic serum sickness
-Some aspects of clinical autoimmunity
-Certain features of infective endocarditis.
What are the complementary and non-pharmacologic treatment options? - ANS-Avoid
the allergen
-check pollen count, keep window closed, use air filters
Cool compresses 3 - 4 times daily
do not wear contacts when eyes are irritated
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